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nbme20/Block 3/Question#42

A 13-year-old girl has an episode of severe ...

Epstein-Barr virus genome

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submitted by ms2991(2),

FA 2018 page 165--> EBV is "associated with lymphoproliferative disease in transplant patients"

katsu  EBV also targets B lymphocytes +  




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submitted by nickybeezle(0),

Human B cells are the primary targets of Epstein Barr virus (EBV) infection. In most cases EBV infection is asymptomatic because of a highly effective host immune response but some individuals develop self-limiting infectious mononucleosis, while others develop EBV-associated lymphoid or epithelial malignancies.





masonkingcobra  The pathogenesis of post-transplant lymphoproliferative disorders (PTLD) in most patients relates to the outgrowth of Epstein-Barr virus (EBV)-positive B cell proliferations in the setting of chronic T cell immunosuppression. +2