https://www.youtube.com/watch?v=WGWFFN01qkA succinylcholine usually has v fast duration of action bcuz metabolized by plasma pseudocholinesterase. With atypical pseudocholinesterase, decreased metabolism of succinylcholine and thus causes a prolonged duration of action of succinylcholine ----> APNEA
The duration of action of Succinylcholine is determined by its metabolism by plasma cholinesterase. So if there is abnormal plasma cholinesterase (=psuedocholinesterase), it will lead to delayed metabolism of succinylcholine as well as mivacirum, heroin, and cocaine.
Not sure about this, but it seems to me that this is referring to "pseudocholinesterase inhibitor deficiency. It's an enzyme defect that is triggered by NMJ blockers - succinylcholine or curare's.