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NBME 20 Answers

nbme20/Block 4/Question#48

A 24-year-old man comes to the emergency department ...

Lipoprotein lipase

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submitted by hayayah(512),

Pt. has Familial dyslipidemias. Type I—Hyperchylomicronemia.

estefanyargueta  Lipoprotein lipase: degradation of TGs circulating in chylomicrons and VLDLs. +1  
breis  FA 2019 pg 94 +  


type 1 hyperchylomicronemia ( pancreatitis and TG's in the 1000's.)

+/- medblues(0),

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submitted by pg32(7),

Can anyone explain why the lipase concentration is so high if there is an issue with LPL in hyperchylomicronemia?

garima  due to pancreatitis +2  
neovanilla  ELI5? +