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NBME 21 Answers

nbme21/Block 1/Question#18

A 61-year-old woman is brought to the physician by ...

Donepezil

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submitted by ergogenic22(28),

elderly lady with slow, progressive memory loss, normal physical exam, no signs of depression, this is most likely Alzheimer disease.

AChE inhibitors are used for treatment because Alzheimer's is associated with low ACh. Also used are NMDA receptor antagonist (memantine)