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NBME 21 Answers

nbme21/Block 2/Question#45 (34.6 difficulty score)
A 3-year-old boy is brought to the emergency ...
Synthesis of factor X (Stuart factor)πŸ”

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submitted by mcl(598),
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tNo seur if sith is eht ihrtg wya to hntki btaou i,t tbu fi TP and TPT rae hotb opdrneo,gl tihs stmo iylkel mnase eetrh is a ebrmopl htiw the ocmnom wtaahpy a(ak ctarof )X.

temmy  exactly...i just thought the problem has to be where they meet or somewhere similar to both..hence the common pathway 12(PTT Heparin) 7 (PT, Warfarin) 11 9 10 5 2 1 In my head, both sides are looking for the perfect 10 +  

submitted by msw(1),

theres a uworld question like this ... ,, rivoraxaban and other factor Xa inhibitors prolong pt and aPTT but they dont affect thrombin time ... while direct thrombin inhibitors prolong PT aPTT and Thrombin time , also unfractionated heparin prolongs aPTT and Thrombin Time (Theoreticallly it should prolong PT too but in the test the PT reagent contains heparin neutralizers that minimize this effect ) . sorry if this veered off course a little

submitted by usmle11a(75),
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i ddi htsi grtohhu o:eilaninmti

ca, dna D i;rntinsic T↑PT lyon

)B which is aclytaul the 2PPI; vvleinod in Gq siigglnna