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NBME 21 Answers

nbme21/Block 3/Question#7 (47.0 difficulty score)
A 65-year-old man comes to the physician ...
DNA fragmentationπŸ”
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 +18 
submitted by feronie(18),
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reOocmyitch = ↓ etetersosnto iruconodtp = ↓ TDH &=;tg arepstot cesll udngroe tpissapoo. i(Tsh smhnimcea is msairil ot usign steΞ±au5-rced lsebrkco to tarte H.B)P

ppooAssti is crzhaeieardct by AND tforaamegtnni osipnyk,s( rysrrkaeio,xh )sa.yoskliyr

hungrybox  DNA fragmentation histopath: https://i.imgur.com/nxYW8vL.png Note that degradation in apoptosis is progressive. From pyknosis -> karyorrhexis -> karyolysis. Aka condensation -> fragmentation -> complete dissolution. +15  



 +6 
submitted by cytocoins(6),
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Whti eht podr ni eenoesotsrtt nad( eeortfehr ,)THD seom of het rtstpaeo eclls liwl eoundrg sa.ptsopoi opotisAsp = NDA neiraongfmtta 0(81 pb m)eensts.g




 +2 
submitted by _pusheen_(6),
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rivtAe,elntayl lla teh hroet iopntos tnioepd to tsghni taht wdluo ulacytal aiscenre ntotoesrtese cpundrioto dna tsi ;efctfes oryheimccot olwdu oysovubli not do atht.




 -7 
submitted by step1soon(43),

Orchiectomy: One or both testicles is removed through a small cut in your scrotum. tissue removal from body β†’ no nutrients β†’ cell death

  • hall mark of cell death = DNA fragmentation