lovebug
Cholerae's exotoxin does not invade mucosa. but just permanently activates Gs according to FA.
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lovebug
Same mechanism[Increase cAMP] : 1) Labile toxin of ETEC,
2) Edema factor of B. anthracis, 3) Pertussis toxin of B. pertusssis
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submitted by โmcl(671)
Vibrio cholerae is a gram-negative, comma shaped bacteria that can cause watery diarrhea. Cholera toxin functions by activating the Gs proteins --> increasing activity of adenylyl cyclase --> increased cAMP --> increased Na+ and Cl- efflux --> diarrhea.