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NBME 21 Answers

nbme21/Block 4/Question#24

A 56-year-old man undergoes a renal transplant. ...

IgG plus complement

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submitted by hayayah(345),

Hyperacute transplant rejection occurs within minutes d/t pre-existing recipient antibodies that react to donor antigen (type II hypersensitivity reaction), activate complement.

mcl  [Useful figures illustrating transplant rejection]( +  

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submitted by priapism(3),

Per First Aid: antibodies against ABO blood types tend to be IgM or IgG, which is why the answer is IgG + complement and not IgA + complement

yotsubato  IgA also has no role in any hypersensitivity reaction +1