Translocation may result in failure to transcribe RNA because of disruption of a regulatory element (eg, promoter) within a gene.
The affected gene will not be expressed or will be expressed in a dysregulated manner compared to the normal phenotype
sThi sha ot do htiw iotnnr c.siilgpn bemeRrme AGT.G Tshi nituamot ddnueic na AG oelcrs wreeh it was puseopds to e,b os osem fo ahtt itrnon jsut mebeca an .exno
I dtereteinrp qenusc"ee usgrndouinr rfist owt oxnes fo "egen - to maen yhte mstu eb altikng otabu osirtnn. rehTe of het areswn soeichc n'dto ehav hcmu ot od hwti onsir.nt
thta amy otn eb ira hi,tgt ubt lhpse arrwno dw.no Aols ngkinow meso seBa-ihtalsam si eud ot rsnaiatv in nalmabor ipsgciln ph.esl F(A 1902 pg )43
sloa meeermbr that hBaie-almatss is ued ot topin nstmoitau in spelci tesis nda eoprormt nquessece A9F(1 04.1g)p If uoy aterce a itntamou in a icepsl eits uyo lliw ruesyl emss pu eth tercroc RANm ddenee ot eakm a utincnalfo ilog-bnB pitoern. htaT is owh I nswderae hte is.ntqoue
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$279$49As dcdberise ni teh sqniueot s,emt this oatmntui socucr tnwiih na nnotri (a nege esmetng chiwh is csitebrnrda NtAg-RNA;[&]D but ont ra)ttdsan.le ARN sclpgiin m(ye)sezn rbga ARN dan lo“po ti”; na oitnnr is uct uot dna eth oexsn no rhteei ieds fo teh otnnri rae ,ndeijdoa ikle :tshi
etnrie2o1nxnox—n—o &g;t= n1xe2eon—ox
l,yipyaTlc ihst ispngcli orccus at het rvye egdse fo eth ortinn taw(h I otdeedn wtih hte —”“ cehat)r.rca Btu in our ca,es a intmtoau hitwin hte tiornn si inacsug NAR igscnpil emnezy ot ezegorinc a wne tis:e hte lreiscp ctus nwitih eht nrntio tdisea(n fo ta het ervy eg,de sa ti l)hdsou. ,So ew get hsoigment taht soolk keil tshi:
ex2no—rnno—ti1xe
h’atTs a lloytat ntirfeedf mRAN uolce,elm dan s'ti noigg to maek rou nl-βgobi prtenio kloo (dan )evehba alluyfw ng.trsae
$279$49