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Retired NBME Free 120 Answers

free120/Block 1/Question#9 (reveal difficulty score)
During an experiment, a Southern blot ...
Gene rearrangement ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +9  upvote downvote
submitted by โˆ—waterloo(126)
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uoY nac kolo ta hsti iqntsoue .srtteaaylcgli

  1. uShtnero obtl &-t;g- os DA.N
  2. heyt ear nusgi an nanleeeuscod to nftserra sibt, hist oesdnt' erlyal neam giahynnt ot uyo ty.e
  3. cADN si rnipbog rfo nsgeil iao-tnnlosocgblinutunmm rngioe.

sT'tah panmrttoi, buaeesc wno you nwko tehy rea gioolnk at het oatnncst eignor fo inolnuuomlgmbi aka cF fo hte avyeh ca.ihn

So hwy is hsti ANDc ttha onescde cF, nigilhgt pu nylo once in orthe u,esssti tub het aesm NcAD hisltg up etlpmiul stmie ni anle 2 bne(o ?wrm)aor Tsih si ca,esebu ta the nboe rrmawo amnrod ticamrnoebino fo lghit or ehyav chnia r,scocu dan uor cNDA is enptsre in tfdierenf ndarmo intaomsocbin with tgilh caish.n That ifecispc cAND usecqene htye ueds ntd'di ecnhag entbewe hte utisess or neev iwtnih hte bneo omrraw, nda ti wlil ynlo ibdn to the noe gnee s.eecnequ Teh cfta ist' nightgil pu leuipmtl tmeis sltel yuo htat the esam seqnecue si ertnpe,s ouyr qeoutins si wyh os nyma te.ims

solA a dsei enot, snhtuoer stolb are teim gnonus,mci so bsal seu rhteo mdteosh ot do teh meas ghtni ekl(i ),RPC btu sthrnoue bslto are litls eth tesb nhwe ti oemsc to cgchikne gniomonliubuml and T ellc eocrptre gnee tenarrreangme.

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 +7  upvote downvote
submitted by โˆ—sugaplum(487)
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This oneuisqt si kansig otuab JDV nrgmetaeeranr hihcw sehanpp in hte boen o.wramr Teh esegn era lla ppcodhe pu acebesu hte B clle si tygnri ot areenetg a uquein nicoabitomn rfo tis eopterrc
p ilsem ccnoet.p..s odd gnwodri

hCrpate 3 of how" the nmumie sstmye "swokr - oesmeaw okbo

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varunmehru  ni teh uesotnqi t,mes htye aer anksig tuabo a tansntco .oerngi JDV arntrmeergena is rfo eth raieav.lb It odt'ens amke sesen :( +4
sallz  tBho the nntscaot v(ahey ahscn)i and het glhit sahnci oudreng egne .amragrerenten hTe yehva ahnic ougndrese DJV)( drmaon teasmioonicb,nr eiwhl eth lihtg niach rgneudo VJ aormnd coimntaobins.er oS neeg reaemnrngrtea ducol wrok for tboh oisgn.re +13
azibird  eTh otcnntas ongier eosd tno edgnuro obtarmicin.oen asTt'h hwy its' edacll oscantnt. t'sI ujst rhgti etnx ot eth aralibve noierg hghot,u os heyt tge sedsrpexe etrtgoeh sa eon ertno.ip s'hTat yhw teh eblsanntde-taocl DAN neigro si eaavlirb lnghte .ehre +4
chaosawaits  oYeu'r gtrhi tath het nsotcatn eonrig si not ergdgoinnu mnooai.crienbt Teh eptullmi asdbn rae nto do to nnttacos ioerng arrennaegrtme; sit' due to hte raabevil ihcan rgrgairanen dna hten het ANDc perob htta is ccpfesii ot the anscntto rigeno ahcseatt to haec of seteh argernenta,esmr inesc it n'saht dnahcge +



 +3  upvote downvote
submitted by โˆ—em_goldman(31)
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I ibevele (lps rorccte em fi m'I nrowg) ouy udlwo hvea lraimsi rSotnheu olbt slutres esen in B sellc gonuirnged taocsim hotntuirmape,y tbu tath skeat pcael ni teh sandyreco yoidlmhp t,useis not ni hte nbeo a.womrr

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madamestep  I tkihn uory'e hgtri +



 +1  upvote downvote
submitted by โˆ—azibird(279)
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I edra siht uintosqe sa glinaynaz nnlugluoisimbmo ni het noeb wmrroa vs uto gicluicarnt pirrallepe.hy I own eeliarz itsh si owg,rn and teyh era ustj ingzalnya het ADN of fetirdenf lelc aploit,pnuo keli a toptyeaceh rfo xalep,em tno mngnlboumsluoii tseepnr ni hte .velir

ihtW tish aeelcrd pu, I nac ese who JVD)( mnnbtioarieoc uocdl eakm eht lgniroai DAN inesoct tr.srohe tuB ohw codul (VDJ) imtoebonarcin lyspiobs amke eth AND intesoc renl?go heTre rea sband no eht lge taht rae igerhh lcmeoaulr itghwe in teh bnoe oa.rrwm nioaoRcmibtne loyn tneshosr eth DNA, snemooe elsaep ercrcto e.m

lAos hyw is rehte on ndab in eht oebn mwrroa atth si eth mesa zesi as heiplaprre nab?sd Slyreu eht SHsC ehva ton nodeugren rctei,iaoonnbm heerw is hrtie ?DN?A?

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azibird  reeH is eht frigue fmor alpKan o.gomnmuIyl See who iobareminncto ynlo ekmsa het senecueq orts? hre2gpIt/ojuu/fcrmhsa/.f/tHm:ipnal aK saol sya:s Welih" hvaey acinh enge semetnsg rea dggnonreiu arimooicn,tben eht nyezme lairtemn lnduoceolxdtyriebyoi afatrsreens ()Tdt nlrmaydo rnsitse seasb hoi(tuwt a elteptma on eht ymlretnempoca dsa)rnt ta eht jtncnosiu of ,V ,D nda J emssetgn Nceidonu(-etl idtoa.nd)i eTh rmnoda adotiidn fo het o-enclu edit netasrege lnjunitoac Hedrsvo"wr .te,ieiyv htis dluwo nto ccaunot for the quael epswsiet ihggnnelent fo AN,D wihhc is ycaelrl rfmo sethe ecliboamnreb ns.iut +1



 +1  upvote downvote
submitted by โˆ—hello(429)
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hEcgion 'eltowars@o c.tmenmo

Tsih Q is lsielnaytse ikngas aWth" si hte oiufnnct fo uhrotnSe o"lbt?s

rsAnwe: ehT nucintfo of Shtrueo lobts si ot ckche rfo BRC ro CTR nege ensemrarrgenat.

eeS otowaer@'ls oalntnpixea rof thaw is fecsapilcliy ognig on as fra sa yhw rteeh aer tefinrdfe asdnb ta enefridft cslaep. ,iAagn the raswen ot hist is e"eng "regtrernanema ubt @oaowlrte ixlnpase ni wtih eomr deitla.

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 +0  upvote downvote
submitted by โˆ—bwdc(697)
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hStreuno losbt rae loomnycm uesd in oocgumnlilmai e,isutsd sa het eostnurh tblo lsloaw fro het tdusy fo NAD .siolttreaan Wtha si nlyolmar eon eneg oritnuigcfano ledarte to nimume nugilobsl ni tmos sutsesi tastrnmosede elmtluip ndtffiere adnsb in eth nebo womra,r ecnivtiadi fo eegn rtneeaegrrmn.a isTh is ibscllaay hwo we cretea nwe otbindi.esa cvetaiRe eropcsess rae acollypnlo ui(elmptl ands;b) kumleiea, in ,crtstnao is lnolonocam ngsile( n.abd)

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ali  I tlsil ndoโ€™t neatndrsud hist .noe udClo you vpdorie a ettrbe o?aplnxaneti +1
bwdc  ehT NDcA tga is inatggg a ntsotanc nrogei mmonoc ot unluiib,mmloosng so it amlynlor nlyo nfdsi eht neo ndab dinscrgoenopr to ttah rtcapriual egen eht( sabdn taelvr retnefdif asutmon edu to hrtei iregnidff htwzsgi.e)i/e In het oben moarwr p,mlase htat egne sah rneaadrrge ,ifetls so hte cNAD onlec seidtna stag ellitpmu eentfdrif egnes that rea of eftnredfi szeis no eth egl (aceh neo ahs hatt aesm nttacson nrogei hte NADc is ggtn,aig tub thiw ednftrief fsutf drunoa ti uhsc tath teh oineritrtcs zmynee ash tuc ti up etd.nfrefil)y dIโ€™ eb ahpyp ofr oenseom to etps in dna od a rbtete bjo on that lonipn.atxae +19
em_goldman  A ernthouS lobt arsstt by tguitcn NAD nrtassd at a alrcripuat (rth)os teis adn nirgunn ehmt gouhrht egl itpee,cershsloro so ntideacli DAN qsecensue egt tcu ta het asem siet dna usth are het seam tgehl,n os ehty ear at the msea pcela no teh eg.l If sreeh't ltso of dtiffnere esenqu,sec het rrecnisiott seoendulncae h(et ssiocrs)s cut eht ADN at fneredfti ea,pscl ngeidal to tndsras tath ewre eht same ghlten ylioailrng but are own tosl fo rfifnedte gsnelht tg-&; dfnitrefe cseapl no teh gel. Btu who od ouy wkon shit is hte saem ge,ne ustj whit denrtiffe most?tuina hTe hutSnero blto suse a rbeop ot olok rof a moer icifecps (onlg) igoren fo NAD htta yuo wkon is in hte eattrg g.een So even oghtuh etreh rea tsotinmau gauscin het fcscepi-lssie eslneecoudan ot ctu eth DNA at tfnerdeif pta,rs eth alrlove trrecuihetca of eht ngee is smariil uoengh atht eth rbope cna dni,b tshu we owkn sti' eth emas e.gen nAd( ni ebon raworm WsB,C eth mhmnsaeic ehre is teicnge ergar.armteenn) +2



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