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Retired NBME Free 120 Answers

free120/Block 1/Question#9 (reveal difficulty score)
During an experiment, a Southern blot ...
Gene rearrangement ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +9  upvote downvote
submitted by โˆ—waterloo(126)
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uoY can oklo ta tsih eqnusito llti.tsarcyeag

  1. untrohSe tbol -t;-&g so DN.A
  2. ethy rea uinsg an euaennoelscd to rreastfn ,istb sthi te'dson laeryl nmea ingatyhn ot ouy .ety
  3. cNAD si ipbnorg rfo gnesli unnitbimo-ncolmlunotags .gneiro

'Ttsha ,aitmontrp aesceub wno yuo wonk htye are lgionko at het tocannts geoinr of biougommilulnn aka Fc fo het hvyea .ahinc

oS wyh si hist ADcN atht esecond ,Fc tglniihg up lnoy neco ni rteho tuss,esi btu the msae NDcA gtshil pu luplitme stmie ni eanl 2 b(one rm?wr)oa sihT si a,cebesu ta teh bneo romwar rnaodm ocnieobrtmina fo tighl ro havye aihcn ocrs,cu adn rou NAcD is resepnt ni fferndtei adormn acniibtomson ithw ilthg nasch.i taTh iiscecfp AcND euncqsee heyt euds dnitd' cgnahe ewbeetn teh uetsiss ro neev inthwi het eobn wmrroa, nad it will oyln ndib to the one egen .cuseeqen hTe tfca its' ntghgili pu lpmtueli imste letls uyo that hte meas eqenuces si ter,snep ouyr neiuqsto si why so aynm mte.si

lAos a isde ,otne uroenhts otlbs ear meit s,nomicnug os sbal ues ertho seotdmh to od teh eams gniht ei(kl RC),P ubt seuohtnr otslb rea sillt the sbte hwen ti mesoc ot nghekcci inmboilnolumgu nda T clel eerpctor enge emerreatanrng.

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 +7  upvote downvote
submitted by โˆ—sugaplum(487)
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Tihs eqitnosu is naikgs autob DJV netraraenegmr ichwh pshpena ni hte eobn .orrwam eTh gsnee aer lla ppocdeh up baescue het B elcl si igrytn ot ernteega a iueunq mctiinonbao for sit tpoercre
ep imls net.scpo.c. odd wgrnido

rapheCt 3 fo "who hte mmineu etmsys orkws" - eswamoe obok

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varunmehru  in hte qoiuesnt smte, eyht are knaisg uatob a otncatsn eino.gr JDV tenrgreearanm si rof eht birl.aeav tI ens'dot akme eessn :( +4
sallz  hBot eht snotnact yav(he csni)ha dna eht tgilh aisnch rgneudo gene re.mtrnarnagee Teh vaeyh china ngdsroeeu ()VJD dmorna oimscnn,rteibao lihew het htgil ancih eguodnr JV adnmor acbreooinimt.ns oS egne earretngmnear clodu rwko rfo thbo inreo.sg +13
azibird  eTh ntcstano ireong eods nto gdronue in.aroineoctmb Tt'hsa yhw t'is alldec snca.nott Is't sjtu thirg ntxe to eht aaielvrb nrigoe otug,hh so yhte teg dxepreses ohretetg as oen tip.neor a'shTt why eth oedtlnbas-ctanel ADN reniog si eibavlra thgenl here. +4
chaosawaits  or'ueY rihgt thta eth ocnsantt gerion is ton ggdnrueoni nncimreoatbo.i hTe letmulip asbnd aer tno od to cotansnt geinor ;mtnarreernega 'sit eud ot eht brilavea inach nerirggnraa dna tehn eth ANcD rebpo ttah si sicefipc to teh nnstatco engroi stataceh to ahec fo sheet neanemrartgser, necis it hstn'a engahdc +



 +3  upvote downvote
submitted by โˆ—em_goldman(31)
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I beieelv s(lp ocrtcer em if 'mI wrog)n oyu wlodu avhe irlsiam tenSruho lbot lseturs nsee in B cells ueniggdrno mtaiosc hmyauontr,ptie ubt taht stkea cleap in teh cdenoarys idolhmpy st,uise not ni eht onbe .oamrrw

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madamestep  I nkthi ouery' gitrh +



 +1  upvote downvote
submitted by โˆ—azibird(279)
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I dera siht iqutseno as iagznlyan ulimonngoibumls in hte nebo marrwo sv otu langccuirti lelyeprrih.ap I wno zelriea itsh is rng,ow adn teyh are usjt aiynglzna het NAD of dtfierfen llce ,itpnuaoplo klei a petheoycat rfo mpee,xla not olnbngmuioluims seenrtp in the ilver.

hitW ihst leceard ,pu I cna see hwo JDV() imaotrcibenno ouldc mkae eht orlniagi DAN icstnoe orts.ehr Btu how coldu )JV(D onoriamietncb bssoypli make the DAN eontics r?egonl hereT rae adsbn no het leg taht aer gerhhi mleualcro wgehti in eht bone wmao.rr inoRbieamntoc noyl tshosenr hte ND,A moenose easple ecorrtc e.m

Also yhw is treeh no nadb in hte obne mwraro that si eht meas size as herlireapp b?sdna Syelru het HsCS hvea ont edngernuo ionnimretoba,c erhwe is etirh ??AND?

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azibird  erHe is het rugeif mfor palnaK og.Inmylomu See who cobmnianeorti ynol amkes hte scneeqeu tsero?h r/ftrsfI.mp/um/hg:tiju/aoHc2a Kapln aosl sa:ys lWhie" aehyv cnaih gene megesnst rae ruoegigndn nrotm,aoibcien eht eeyznm rlmeinat tbendoxieyluodiylocr asenerftras Td(t) ondlrmya rsintse ssabe ttwh(uoi a tletaemp no teh teocmlmepyran srd)nta at teh iojcsunnt of ,V D, nda J segetsnm -e(leicNtondu ai).itodnd heT mnardo naddtoii fo the nucleo- ietd sreeteang atlocnniju r"yivHro, we.sdtveie tish louwd otn tccouna for het alqeu seitewsp nhenelgintg fo ADN, hichw is lalyrec fomr heset bcaloimbrnee tnuis. +1



 +1  upvote downvote
submitted by โˆ—hello(429)
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gionchE oloters@wa' metmocn.

ishT Q is ltelsiynaes igkans tWa"h is the coitnnuf fo nShetour "tbos?l

ens:Arw ehT foncunit of rStuhoe lbsot is to ecckh ofr BRC or CRT enge msrtenaagrrene.

eSe o@torws'lae aexnilntoap for htaw si ycsalelfiipc ggnoi no as fra as yhw heetr ear fitrefedn dasbn ta eerdfnift clpse.a nAai,g het aresnw ot shit si "egen mtrengaranee"r tbu a@lotorew anpxlesi ni iwth reom .ltiaed

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 +0  upvote downvote
submitted by โˆ—bwdc(697)
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rtuSheon sbtlo rae mlconomy dsue in ioilgumclmaon eist,usd sa eht ursetohn bolt aolwsl ofr eth sdyut of AND tinlera.otas Wtha is nmyarlol noe enge nigfctounoira taerdle to enmium lougilsbn ni otms esussti mtstsaerdeon ieltmlup rtiefendf sbdna ni het bone mrrao,w vcidatniei of gnee eae.grtrermnna iThs is aablicsyl how ew eceatr wen asibodin.te vReicate scspeseor rae llloyaocpn muple(til na;bds) ual,eemik in ts,oacnrt si olncomalon n(lgise nd)ab.

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ali  I itlls tnodโ€™ ednsdnrtua htis noe. olCdu uyo ivderpo a ttrebe itlapoex?ann +1
bwdc  ehT ADcN agt si gntgaig a nttonsac rgenio moocmn to l,golnmnobimsuui so ti orlyamnl oyln sndif het oen dnab iorenrdponsgc to atht racpauirtl gnee h(te bnasd arvtel rtefidefn mtnsoua ude ot erhit ingirffde .ewitzi)hg/se In eht neob wrmaor ,sempla ahtt gene ash engaraerdr tlf,ise os het NAcD oceln tnasied agst lulmipte ftiefdrne nsgee hatt are fo efetrfdin eizss on eht gle (ahec neo ahs atht same tscnnoat girone hte cDNA si gggti,an but wtih dferntefi sffut rdnauo it husc ttah het tieroirstnc meeyzn sah cut ti up dti)f.enfyrle Iโ€™d be ahypp for mnseeoo to spte in adn od a btteer jbo on htta enaxatil.pno +19
em_goldman  A ohnetruS tlob srtsat yb nttigcu DAN rsatsdn at a rrualtaipc ots(hr) iest adn ginnurn tehm gutrhho elg sthporl,roeicese so eidinltac AND uqsseecne etg tcu at the mase ites dna suht are eht aems ng,ethl so hyet rae at teh mesa lapec no het eg.l If 'stereh tslo fo edreifntf uee,csnesq the itorrntcise neelsnacoedu e(ht scosisr)s utc het DAN ta ffniedter lcpae,s aenigld to ntsrdas taht erwe het meas gehltn ryiaolnlig tbu era won tlos fo ritnffede shtleng &g;t- rfdeiftne secpla on teh leg. utB who od yuo wkon tihs is teh smea een,g utjs ihtw ntireeffd oa?nsuittm Teh etShnour lbot seus a opebr to kool rof a oerm iefscpic o)(lgn ongire of NDA thta oyu nowk si ni teh rettga egn.e So neev ghhotu rehte ear umtioatsn nagsciu eth eif-eilcsspcs ueaeoesnclnd ot utc eth NDA at ftrdiefne pars,t eth allervo thctucrireea fo teh neeg is airlmis hogneu htat het boepr anc i,bnd usht ew know 'its the msea eegn. d(nA in ebon wamorr CBW,s teh cmmiensah rhee si tinegec rrnegea).mtaern +2



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