share email twitter ⋅ join discord whatsapp(2ck)
Free 120  NBME 24  NBME 23  NBME 22  NBME 21  NBME 20  NBME 19  NBME 18  NBME 17  NBME 16  NBME 15  NBME 13 
search for anything NEW!
NBME Answers

free120/Block 2/Question#17 (10.0 difficulty score)
A 5-year-old boy is admitted to the hospital ...
Inability of leukocytes to kill intracellular microorganisms🔍,📺

Login to comment/vote.

Tutor box

Members from the Leaderboard offering 1-on-1 help: Want to be listed here? Email us!

submitted by benwhite_dotcom(573),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

upeMltil nscntoiie.f ecseAs.bss nhTe you ehar esaredcde ovidiaext bturs dna dieelmyatmi hitkn HNADP esaoixd eiincefdyc aak hrcCion uaulmogoarstn aseedis, icwhh ceussa urnceetrr ssaemnobgfc-irs scieofnint ued to the iilnabtyi to lkli sgdeinte igsrmnsoa ceasbeu fo hte iibnaltiy ot erntegea pureixesdo aldarics.

jean_young2019  Then why the choice D, “Inability of leukocytes to ingest microorganisms“, is incorrect?Moreover, Staphylococcus aureus is not an intracellular microorganism. Thank you for your help! +  
houseppary  Because in CGD, the macrophages are capable of taking in bacteria but aren't able to do the oxidative burst required to actually kill them. So the macrophages just house live bacteria which leads to granulomas full of walled-off but not dead bacteria. And S. aureus isn't intracellular as part of its normal life cycle, but being eaten by a macrophage isn't part of its normal life cycle. Whether an organism gets eaten by a macrophage isn't part of the consideration of whether it's intracellular. +6