need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

Retired NBME 16 Answers

nbme16/Block 2/Question#27 (reveal difficulty score)
A 4-month-old boy is brought to the physician ...
Chediak-Higashi syndrome ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags:

 Login (or register) to see more


 +2  upvote downvote
submitted by โˆ—cassdawg(1781)
get full access to all contentpick a username

Giant granules in neutrophils and eosinophils combined with immunodeficiency (recurrent infections) and partial albinism is characteristic for Chediak-Higashi which is caused by defect in the lysosomal trafficking regulator gene [FA2020 p116]

get full access to all contentpick a username
fanderina  but why is the rough ER dilated? +1
kaymin1234  Due to a trafficking defect, the proteins in the rER can't go to the golgi, so increased protein in the rER will dilate it. +



Must-See Comments from nbme16

bingcentipede on Cerebral edema
zincy7 on Gastrin
cassdawg on Kidney
medninja on Lysosomes
cassdawg on Sildenafil
cassdawg on Feces-contaminated soil
cassdawg on Presence of an internal ribosome entry site
cassdawg on Peutz-Jeghers
hungrybox on Induction of cytochrome P450 enzymes that ...
andro on Antagonizes VLDL-cholesterol secretion
bingcentipede on Decreased function of Na+โ€“K+ ATPase
bingcentipede on Glyceraldehyde-3-phosphate dehydrogenase
cassdawg on 46,XXY
bingcentipede on Grade 4/6, holosystolic murmur heard best ...

search for anything NEW!