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NBME 18

nbme18/Block 3/Question#48

52 yo man, chronic pancreatitis

Colipase

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submitted by breis(3),

Colipase is a protein that functions as a cofactor for pancreatic lipase, with which it forms a stoichiometric complex. It also binds to the bile-salt covered triacylglycerol interface thus allowing the enzyme to anchor itself to the water-lipid interface.