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NBME 18 Answers

nbme18/Block 1/Question#18 (reveal difficulty score)
68 yo man, chronically increased hydrostatic ...
Benign prostatic hyperplasia ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: renal

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 +9  upvote downvote
submitted by โˆ—adong(144)
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Increased pressure is in the Bowman space (NOT the glomerular capillaries) so the only pathology listed that would cause backward build up of pressure is BPH

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peyerpatchkids6  Does anyone know why its not diabetes? +1
michaelshain2  because the NBME said so, obvs! +3
cbreland  Diabetes would have non-enzymatic glycosylation causing increased GFR and hyperfiltation. The stem is referring to increased back pressure (Inc hydrostatic at bowmans space) which alludes to decreased GFR +1
victorlt14  @peyerpatchkids6 that's because NEG of the efferent arterioles could increase GLOMERULAR pressure; No increase in BOWMAN'S space pressure; That would have to be due to one of those post renal azotemia causes. Made the same mistake. +



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submitted by โˆ—breis(56)
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I put CHF, still not sure why it is wrong over BPH, but my reasoning is that BPH causes obstructive urine flow --> Hydronephrosis and once the urine has been made it can't be redone and is like filling up a damn with water. Straight Stasis. vs CHF there is protective mechanisms in place for a while until frank CKD.

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pfebo  This is a case of postrenal azotemia. BPH is the only available option tbat causes it +1



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