NBME 21

nbme21/Block 4/Question#36

A 45-year-old man comes to the physician because of ...

Chondrosarcoma

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submitted by beeip(7),

This review suggests that enchondroma and chondrosarcoma are unable to be differentiated on histology alone. According to Orthobullets:

"unlike enchondroma, most chondrosarcomas have non-mechanical pain (rest pain and nocturnal pain)"

Guess this diagnosis is made on history.