NBME 22 Decreases the luminal permeability to Na+ in the collecting duct (NBME Answers)

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nbme22/Block 1/Question#4 (reveal difficulty score)
A 48-year-old man begins furosemide therapy ...
Decreases the luminal permeability to Na+ in the collecting duct 🔍 / 📺 / 🌳 / 📖
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submitted by ∗hello(429)

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irtenSonalpoco adn epelnnreeo ear apgtmasunsisropi- ituerdccis tath bihtnii het /NKa .TPsAea NK/a TsPAae is on eht tebaalraosl arbnmmee. Nneo of hte nresaw heicosc tif thiw s.ith

imdrelioA adn enetaritemr aer alos opmutngsap-asiirs eur.disitc The amhcseinm si ot cblok ENCa nnsleahc no teh mnaillu nm,rmeeab htis si cocehi "B".

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submitted by ∗j000(17)

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taoocrilnnepso and lenerpneoe ear lroanosetde ptrcreeo goinatnsat h(ety ckbol teh tefcef fo neoredatslo by knbogilc eht aeobalasltr /KNa ePsaAT ),mpup itsh is ton eht emsa hgtin sa lkoigbnc a lselrtbaaao K+ nh.anlce yehT okclb and eacesedr the tsospiamu ncdino.cout eTrhe is no ebaaltsralo +K anchlne

if eth A)( reew to ysa dceaer"es +K cicoodnunt ni nloelgccti "cdut ahtt hgtim eb etrcroc

so B)( si rt.eorcc iteanemTrr nad emairilod obclk +Na nehnlca on icaalp mau(linl s)ide esid, ecdaesre pyaeetlbrmii fo +Na

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submitted by biliarytree220(13)

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uSdlho ues a musprsi-ngsotaiap iecrduti (FA 5)91. eeTrmtniare nad edliraimo wrko by kgnlcbio NEaC hl.scanen

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submitted by just_1more(1)

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I tog ttah it endede ot be a iuasspotm naspirg .eiicudrt sI eethr a sarnoe it notacn eb an nldaotoeesr iato?nagtns I ehcso sbolkc altaboreasl +K chsannel as eehts cseeadre het aertsaalblo ae/aAT+/+PsKN eabcuse het nordgiw of eth etccrro rsawen did ton emka ssnee to em -- sausinmg tehy were noigg for an NEaC keclrob nd(a hatt crsedeeda ulailmn mteilapbirey edsiiacnt htta a+N ldwou eb nmriignae in the uml,ne ton neamnrgii in hte panliipcr clel as I iingorayll h.gotht)u

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luckeroo I kinht eht esaorn ’sit a g-ostpuriapnaissm rtucidie ehrart hnat an oterdnleosa ottanisang sha slse to od wiht yhw eth dalootnsree gonatniast tannoc eb udse dan emro to do iwth eht ctaf atht a rtsasgipu-oapsinm tiercdui lwdou eb reom fo a strlf“enii-” necjtdauiv ediicrtu rttaee.mnt +2

luckeroo As orf eth rwsane ,ochice aptioumss gpinsra distrcuei iahcvee itreh vreoall laoaor-stnetedin cfeetf by tietmyeoicvlp ihbgintnii doltsaenoer rctrpeeos on the riesattnilit deis ean(dsirceg the aaA-KseTNP/ teefcf of uithgnns aN iton het do,bl)o tehbyre iredcgnase eht eigatrdn orf dumsoi to renet eth llec rmfo teh nlmalui ,tapecs ilobcgkn .ENaC +10

yotsubato herTe si on cush itghn as sal"rtolaBea K ah"Cenln heter is noyl tbsaellaaor oSmdui Psmustiao pmusP hcwhi aer oldctnloer by .edeoaolsntr AF gp 375 +11

nwinkelmann b@yutosota .O...LL yhw tn'ddi I hinkt of it thta whta!? (yb the ,wya taht LOL is ofr .m)e The yoln easltborlaa K hnaelcn si het rhpnneo abse(d on eth strif aid e)ipurct si in hte ichkt canignsed mibl of the oolp fo .nelhe +1

hello rnotincaooplSe adn epolreneen rae ssrpnoagiuitmsa-p utreidscic atth ihbitni eth aKN/ as,AePT so 'Im ont esur thaw orlock@eu si rigernrfe ot. oeplocniorSnta adn orepenelan era ohbt LADO ntaoKsaa.tnN/gsi aATePs is fnduo on eht atosaalbler naebm.erm eoNn fo eth swaner heiocsc ift ihtw sd.lh Aeriimito nad itetameernr era olsa augriapmss-ipnsto rusciite;d ither imhncames is to block NaEC anelnshc on eht liamuln aemnber,m hsti si ieohcc B."" +2

rxfit omFr tzuKnga Baord wive:Re ltScnooarp"eoin adn oneepnelre are deoitrs avdvsiirtee dna atc as arplomiaocchg saigonstant fo nseadeoltro ni eth elonictglc s.ubtlue yB boimcgnin htiw dna blgkncio het rultenclaalir edslaorteno rtpeer,co ehset rsugd uredce eth xrnespsoei fo engse htta ecod for eth lheitalpei sdiuom nio eachlnn (N)aEC nda Ka++/N PsaTe.A doimAielr nad iearnttemre atc by gbknoicl teh ECNa miodsu sanenlhc rF(uieg )5–.51 heTes( rgusd od otn lbkco aNI seanhnlc in leeibxcat snemeamr.)b plirnntaocoeoS adn nleeoenper have olsw oestsn dan fseotfs of atonic –4(227 h). deAirloim adn ierremtneta ahve soartiudn of nocait of 241–2 h". oS hbto pigasnK-r epsbyust rae yclhlcaeint otrcer.c +1

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submitted by volleyboy119(1)

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tI ds'teno erattm hhcwi -iasgutaspmpsonri ctreuiid uoy esu. oYu acn lslit egt ot tshi wsr.ean rlseotdnoeA ynlormla esgatluurep /KaN eTPsAa in teh piilcnarp clels of eht CD, rdaeecdes +aN ir,rlecyaallnlut hcihw sedal ot enieracsd CNEa atvyt.iic Sp/lneeacnieopnooroeernlt will hibtiin shit gniorpetualu of NC,Ea eailndg to desreacde reitbeyalmpi to N+a in eth .CD

bOv elmoiaird nda trteiraemne lwli boclk ppicrnail clel Na.EC I'ts all ni het msea cslsa os ythe will lal eadl to hsit fteecf ):

AF 1029 gp 375

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submitted by ∗usmle11a(102)

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ceosaronplonti stac sa an setornealdo insgantota hwcih sname garneedisc N+a aielrmybitpe

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j000 i ktihn yrte'eh ngrrerief ot ienmreeatrt nda demiiorl,a otn trcoenlnosiaop n acnposortloei eds'ont alltacyu erdeseca Na+ meitlbpayire +1

jackie_chan 0j0@0 tI dsteno at,rtme rpsio nda ida/neelieitermarmotr hvae a noommc eeftfc of smgenis tiwh lANosCeornd.teE a pulgursteae C,aEN priso duowl thiibin thta so in eceftf duwol eedescar nuallmi irlaiebpmety ot Na ni duct eud to ewref aENC nlnaesh;c naeermtriet odluw cbklo teh nhnelac t,deyrilc mase fefe tc.dmoesdls./onuimrpi/ppat/tteiikurpdt/twbmew/uaehin.tg_auk_sahcurpiesd:hp. +1

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