NBME 21 Amphotericin B (NBME Answers)

Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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eulR of muth/structbho

seousniroN flguan n:oicntsife ttaer thiw ae_oznolc
siSeuro ugfnal initfcenos (g,e sudmipenmmmcoooir intapset tihw dntesmsiaide if)ntocen:i treta with ihrnoptmcaie B

odildtAian nfoi

Teh amin lsescas of nnfuaigalt mineitdaocs rof mesul du:nclie
leonPsey e(,g hoapiemnrcti B, t)nnatsiy - dniB ot olgesetorr lmeouelcs ni nufgal llec smnrbee,am acitgnre orsep and isnuagc lcle ilsys
aeorizTls (g,e lo_e)onazc - tneePvr the sihtsyesn of oeoeg,rrlst a tmooepcnn fo nguafl cell rnesmbmae
dascioncEhnni e,g( uoncsap,fnig uiginfc)mna - hitbIni het nsstisehy fo c,ulnga a dolacyrsapiceh eptcomnno of flanug clel laslw
erimiPnsydi g(,e yitec)Fosnlu - dteCovner to fiacluulo-,rr5 hhicw ehtn isinhitb unaflg RAN nad einrtop snhyestsi

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jcmed Clle Mabnmere = mrAntcoieihp &mpa; eNns Citlyatl WLAL = pi nuonsafgTCo ton mxi ehtm up I ysa ot smefyl I"'sT eth NGIUNF LCLE AL"WL +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

+5 upvote downvote
submitted by ∗hungrybox(1277)

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yM eoiniprmss fo mirtAhconepi B si that t'si eth BGI GNSU. It histrgta up aaktstc eth solsret in hte nufig almpsa remmane.b

nwhieealM lli hctib gsrud ielk zloea-s jtsu hinbtii lotesr eyhss.tnsi naeit-riebf(n X neslt,roola aseoz-l X glorerseto)

nugiFns X llce llaw s,tsseiyhn iynecuftols X liunecc dcai th.isssyen

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et-tu-bromocriptine ueRl fo tsuobhoitro umusecrhsN/:nt uglfna iocntnfs:ie etrat hwit oeanuzri Soseclo_ fgnalu niencotif ,ge( sdonoemrmiumipcmo aeitptns hwit dtiieemsdsan )if:oitcenn eatrt itwh aonipcmhiert l andoBdiAit efoin Th amni sacsles fo gnaiulfant isenmdtaoic rfo mlsue e celPneou: idlsy n (e,g itaecnhrpoim ,B atty)inns - idnB ot ooergtlser ocsuemlle in lufang ellc m,reabmnes iganrcte soepr and uncaigs llce lsTlrz sei sy oai (eg, leoz_n)oca - etnrvPe hte ehstnyssi of teeooslrg,r a teocmopnn fo nafglu llec sdineasn emnch o bicnErma (e,g cu,gpsinonaf i)gmnncfaiu - ibtihIn the shseyints fo cn,luga a aydpierhclaosc tnoenmopc fo uagnfl clle w limi ssnlPayd eri eg(, eyoluis)Ftcn - vrneCedto ot luiucrfa5rl-o, hwchi hnet itbsiihn nufalg ARN nad orintpe hy ssitesn +2

et-tu-bromocriptine pRppip teh ,gtnfomitar tub eflhuploy teh deai estg sacsor +

et-tu-bromocriptine xieFd ,ti see mmnot!ec +

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