NBME 21 Amphotericin B (NBME Answers)

Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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eRul fo u/tchhotrmsbut

ssoonrieNu afulng ctfnn:oisei ertta itwh _zcoloena
rSuseio fnluag efntisnoci (,eg rdeoonpmmimicsomu tpenista htwi eddiistansme fonei)n:cit aertt with mierntochipa B

oatnldidiA nofi

heT inam ssesacl fo gnaatulfni saoimidentc rof mlesu ncdleui:
oyselPne ge,( pianriteocmh B, tnts)iyan - dinB to setoleorgr uecelslmo in glfnua lcel snrmee,abm ringtcae rospe nda isugcan llce isyls
elrzoasTi eg,( oz_)ocaeln - tevernP eht hsniyetss fo setrolgo,re a ootncmpne fo fanlgu llce emaebnmsr
incdEohancisn g,e( u,ciafgspnon ngificau)nm - biInhti the tssniyhse of ,cgalun a slayhdiecrpcao onnmtcpeo of nflgua lecl wslla
sednrPiiimy ,g(e )tnieoclusFy - oeenCdtrv ot rluarif-5,ulco whhic ethn iiitbsnh alnfug ANR nda inrtpeo sitshenys

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jcmed leCl meraneMb = Acinptimheor a&;mp lNeintsC ylat LWLA = gpfCunosTonai ton mxi etmh up I ays ot esymlf T"s'I teh FNUING LCLE "LWLA +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

+5 upvote downvote
submitted by ∗hungrybox(1277)

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yM mpeissnoir of mcntiohAperi B is htta si't eth BGI NSGU. It tratishg up skcaatt teh retslso in het ugnif palsam .emmaerbn

eniewMhal lil bhtci drgus keil ola-zes usjt tbiiinh tserlo nehyss.its eiiae-tnrbfn( X arslloo,nte oaelzs- X rl)tsegrooe

nuFsgni X elcl lwla tyesissn,h oifyntcsleu X icculne daic nsiyes.tsh

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et-tu-bromocriptine lReu of ntsuuhi:rhteb/msosurtoNco lafung sc:nefntiio rteat ithw nlcazseu reiooo_S gfuanl ieoctnfin ge(, irmemcdouiomomsnp istepant ithw demsdsniteia fnc)o:neiti tater tihw iponricmeath aB Adtdnoiil hienoTf mina ecassls of ntnugaaifl idocstaimen orf smule nesuonlecd: yePil g(,e iteharocnimp ,B sytn)itna - Bidn ot tloroesgre cmeuslleo ni gulanf ecll nrambeme,s gneacrit psore and nusgcai cell se isl siloTrayz (e,g eoc_a)nolz - enretPv the issehynst of ,oerltegsro a pnotomcen fo gnlfua lcle ni nab Eicmcsnseedhonamr ge(, ipfcogsnun,a cufnianmig) - thnIbii eth sesshiynt of nlucag, a cipalorhcaydes ompoenctn of alnfgu elcl iyiei am lPwl rdnss g(e, tunslyFoeci) - eCornetvd to rlauiofcru5l,- chwih tehn itsiihnb alfung ARN dan nietrop yishtsn es +2

et-tu-bromocriptine pppiRp hte tntmrgioa,f ubt lolepyufh eht aedi gtes srscoa +

et-tu-bromocriptine eFdix ,it see cm!enmto +

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