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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm micro

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 +12  upvote downvote
submitted by โˆ—et-tu-bromocriptine(140)
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uleR of hsbr/uchutotmt

  • siosoNrenu gnaufl ieoncs:itnf ttare htiw zac_leoon
  • sSioeru glaunf itnosiefcn ,ge( mmripnosmomocueid tteasnip tiwh aidesnidmets eino)nci:ft atret thiw itrhampecnoi B

Aladitndoi ifno

  • Teh aimn lsssace fo nnuiftglaa miotadcsien rfo mules lu:ncdei
  • nyesoPel eg,( arhcnmtieiop B, niasy)ttn - diBn ot eloersortg leuslocme ni lganuf lecl ee,msmarnb rgincaet rsoep nda uasnicg ecll ssyil
  • irzseTaol ge(, lzoe)an_oc - rveentP eth hesnssyti of lgoosrt,ree a tmeoocpnn fo fuagnl llec ebaemnmrs
  • cahcsdnEnoini ,ge( ,panscniugof fmniu)naicg - nhbtiiI teh sthnsiyse fo lgnuc,a a loschdayprecia ocnopetnm fo flagnu ellc salwl
  • Pemysdniiir ,ge( olstnycFeui) - troCdvnee to ro,5ll-aiuucfr ciwhh nhte hnsitbii afnulg RAN and rtipnoe hyessisnt
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jcmed  lelC eebmranM = tcioAmpehinr a;m&p y iaNtClstenl LLWA = fnosiaou npTCg ton xim htme up I sya to fyemls T'"sI teh GUNFNI CLLE AW"LL +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)


 +5  upvote downvote
submitted by โˆ—hungrybox(1277)
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My poniimsesr of nirmpAiohcte B si taht i'ts eth IBG SNGU. tI thtgisra pu katscat the lertoss in het gfiun saalpm rm.mbnaee

ehnwilaeM lli tcibh dugrs ikel a-selzo ustj ithibni rletso insstshey. a-ieifnbe(tnr X lrtosaeonl, l-zaose X orle)rgesot

nFnsgiu X ecll awll hy,isesstn tyuilcsefno X cliencu cadi ssyshtien.

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et-tu-bromocriptine  Ruel fo thsNtuo buonmc:t/irrseuohs ngaflu :ieotsncfin artet whti zelur_oaeoSni ocs lunafg etifnnico (g,e cmomiiporsmmeound teisatpn wtih dndamesietis oetnicnf:)i artet wiht ticeiaopnhrm itiAd oaBdnl o ieTnhf inam casessl fo gtufinnlaa diticeonmsa fro meusl P deeoyun lc:isnel ,e(g tcheiamnoipr B, a)sttniyn - dnBi ot oseortrleg olcmelues ni ugnfal clel esrmmab,ne cgtarine reops nad uigacsn ecll aeTzyr sls sioi l g(,e zloceon)_a - tPvener eht etssynshi fo erortgo,lse a mentopcon of laungf ecll cnimmo hrnsa Eeacsibdenn e(g, opsnugcain,f nmiicu)nagf - iibhnIt the yistenssh of ngca,lu a sadcylchieorap ocnnopemt fo fanugl llce P res wsiiamlnliyd (e,g eliscyn)Ftou - Cdnvoerte ot ,furuc-r5llaoi whcih hent itnbhisi anufgl ANR nad rotpine s sthse yni +2
et-tu-bromocriptine  ippRpp the fittmanro,g tub llhfuopey het daie gtse arssco +
et-tu-bromocriptine  Fdexi i,t ese !mmoetcn +



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