NBME 21 Amphotericin B (NBME Answers)

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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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eulR of /sturchtbuhmto

nuosNsoeri fnluga :seiifctnno rtaet thiw zaeol_nco
eiurosS afulgn finitncsoe g,(e mupioidmcmosremon stpnteai ithw tdiesmeadsni cfton)nie:i terat whti tponcemhriia B

iAotnlddai foin

ehT mina scelsas of angnlfitua aideoimtnsc rfo eusml :cidelnu
leosePny g(,e teiohmnripac B, ns)ttyina - iBdn ot oeetrolrgs semcluoel ni algfnu lecl ,mmbraesen gnaerict oprse nda ginsacu lecl ssiyl
zTeoslria ge,( leo)coanz_ - nPerevt het nssisyeht of gtros,erelo a mctnnpeoo fo nagflu clle mresaembn
iaocnEhnindcs ,eg( nni,gucoapsf nn)mgaifcui - Iinhtbi hte inteysssh fo gauln,c a rcloscepdahyia toonpnemc fo ualgfn lcel wlsla
iyisePnidrm e,g( )nioscFlyuet - roCnvdtee to roulilu-f,c5ar ichwh enht iiinbhts lnaugf ANR nad ntepoir hysinstes

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jcmed lCel enrameMb = Apiremonhtci m;&ap tnNltly isaCe WLLA = Cnugao isoTnpf ont ixm mteh up I yas ot selymf IsT'" eht UFINNG ELLC "LAWL +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

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+5 upvote downvote
submitted by ∗hungrybox(1277)

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yM osmiinpers fo rAcioehnimtp B is htat t'si teh GIB NUGS. It tgarshti pu aattksc eth lorsest in hte iungf apmlsa e.nbmemar

einhlwMea lil itbhc gsurd ekli oalzes- jstu hiitibn lrtseo se.shytins ebainrefti(n- X lo,lronesat aselzo- X ee)rgstoorl

sFignun X clel wlal nessi,yhst elsoicunfyt X ceincul idca i.yenhssst

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et-tu-bromocriptine uRle of ircooo/hruubesthm sunttNs: gunfal fscet:niion etart htiw zcli_euoo noaesSr alfgnu ftiocnine g,(e omiomicmompsrdeun petnasit hiwt ddmtsisneaei nf:oiniect) traet wthi npamriihetoc ltoidi AdnBa Tnihf eo anmi assslce of gtnlufiaan caitmsidone ofr musle e Peuyecnds il:nol ,e(g mtperiihaonc B, nitytsa)n - dBin ot ogteslerro lmlceoseu in fangul lecl e,mramsenb rnetcgia srope dna nscgiua lcel Tisrz soslei lay (eg, _olnezca)o - envePrt eht shesyinst of eetgo,rolrs a onpecnomt of gluafn clel aerancssnnecdbim hniE mo (,eg caosiu,pfnng fncm)agiiun - biIithn hte ntshsieys fo nau,clg a dlporseciyhaca tcpnmnooe of nulgaf clel iP ymlslswdinie ra e,(g Fuoctylensi) - Cteoedvrn to ,5oarlu-rfluic hihcw tneh nsibihit ngulaf ANR dan trionep tssyieh sn +2

et-tu-bromocriptine pipRpp eht i,tfmgornat tub ypefhullo eht deai gest rocsas +

et-tu-bromocriptine edxFi ti, ees t!necomm +

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