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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm micro

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 +12  upvote downvote
submitted by โˆ—et-tu-bromocriptine(140)
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uRle of htr/tsuohbcmtu

  • sneouoNsri nafgul enionfscit: ttera hiwt ceozonla_
  • roeisuS lagunf iestinnofc ge(, mimcoiosdpemnormu inepsatt twih mdndstiesiae not)ei:icfn ttrae hwti tihnmproieac B

dnotdiaiAl noif

  • hTe mnai sclesas of gaunifnlat edsmiticona ofr lemus dle:cniu
  • yoePlesn (,eg rometchniipa ,B iay)ntsnt - Bdin ot oertlroesg lcelmuseo in nlgfua ecll be,rsmemna arienctg peors dan suiacgn lecl iyssl
  • sarziTole (,ge ae_noczl)o - Pteervn het issyhetns fo glrtre,oose a opmoncetn fo flngua lelc aebmrsnem
  • naocdcinnhisE ,g(e nagsno,cuifp au)mcngiinf - hIbinit the sieysntsh of u,lcnga a oelsahayrcpdic pcmonoent of ugalfn clel lwasl
  • rsiiPmdiyne e,g( c)uyotienFls - eedCvrnto to 5-ciu,orlrlufa hihwc enth biithnis nualgf RAN nda iepnotr nestyshis
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jcmed  Clle amMberne = entAchmiirop pma&; la itlstenyCN WLAL = o spgaCuonfnTi ont mxi mhte up I ays ot fyeslm sI'T" hte UNNGFI LLEC AW"LL +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

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 +5  upvote downvote
submitted by โˆ—hungrybox(1277)
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yM irsmosniep of imcnAoipreht B si that ti's eth BIG SGUN. tI iahgrtst up acstkta het eoltssr in eht gnfui amalps er.mbamen

leinhwMae lil chbit surgd ielk azos-el stju nhibiti lrtose s.yhesntsi r-nietnei(bfa X ,tnsrealool lzeas-o X elg)sterroo

nigFnus X lcle wlal ,hinetysss isyftlucnoe X incclue idac stsshyin.e

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et-tu-bromocriptine  leRu fo :theunorcNmuost/bisshtoru gulnfa oeftisnci:n atert whti acoSsze ine_uloro afnglu ntcfioeni eg(, mmueoospicommrdni pttisnea tiwh ndetsasemdii itciof)nn:e atter iwth hemcnitiraop ldtndiiaBAo eThf ion anim clsssae fo finnlatgua imtsoeicnad for elsum leunPd s :oel niyec ,g(e rehtpoiiamnc B, nt)yntais - niBd ot etorlorsge ueecoslml ni fulgan clle am,ebnsrem gtneriac ropes nda aucngsi lcel zsaiiT rysole s l g(,e e_nlocazo) - rtvenPe hte etsnsshiy fo tlr,rsegooe a coemtnopn fo ngfaul llec E nnnechan boarimimesd sc (ge, i,pcnnusogaf amgn)cuifni - Iiitnbh teh etshnssiy of gc,naul a spaocircdalyeh empontocn fo ngaufl clle iwanrll syiedsmiP (ge, teycsFuonl)i - eodtnerCv ot iul,auo5f-clrr hhcwi hten iibtishn uglanf NRA dna orietnp shsyentis +2
et-tu-bromocriptine  pippRp hte ,antmgtfior utb lulpyfheo teh eida gest sarsco +
et-tu-bromocriptine  eFixd t,i ese om!cnmet +


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