helloWhere in Pathoma? I couldn't find it.+12019-08-12T18:43:42Z
almondbreezealso sketchy says that thiazide s decrease the amount of lithium cleared--> lithium toxicity+12020-01-13T15:46:17Z
paperbackwriterAgh confused as well because FA2019 (pg 562) says that thiazides are implicated in lithium toxicity D: +2020-02-06T05:03:49Z
paperbackwriterOOPS, please ignore last comment. I just realized that this Q stem never mentioned lithium. And on top of that @meningitis mentioned that amiloride is used if lithium induced. Apologies. +2020-02-06T05:05:08Z
meningitishydrocholorothiazide is DOC for Nephrogenic Diabetes insipidus because it paradoxically causes an increase in BP by increasing sodium absorption and thus water absorption, Pathoma explains this nicely.
Also you shouldn't have chosen Desmopressin because upon fasting (fluid restriction) ADH is increased meaning ADH is being released Centrally but is not working in the kidneys at the V2 receptors of the epithelial renal cells at Collecting duct.
On that note, Amiloride is used for Lithium induced nephrogenic DI.+12019-06-11T03:21:08Z