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NBME 22 Answers

nbme22/Block 2/Question#2 (14.9 difficulty score)
A 65-year-old man starts using topical ...
Thymidylate synthaseπŸ”
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 +4 
submitted by usmleuser007(370),
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owT jomar mcnhssaemi fo noctai ahev eebn elte:uidcad

1) csyonuiteFl si auirnglnalyft tdeonrvec toni teh cotattysci oiuufrllaorc wichh onsudrege rtrhefu setps fo ctotainvia dna lyflina ierascntt sa hpeiooarps5etnrihouldfi-rtu twih RAN yhbsoesiitsn hstu rngsubitdi hte nludiigb fo nectrai naeistlse etipsr.on

2) sinctyolueF olas nregsodeu virnoenocs oint dohfoopdmuronuyiiohseerxpno5tla-e hiwch ntshiibi gfauln DAN n.eihsstsy

3) mthTadlyiye ethystesan si na mezney that tesycalza the onorciesvn fo nyiedxeruoid omoetnhaosphp MU(Pd) to inhxdeiotdymey theapmpnoohso PT(dM).

ydmnhTiie si oen of hte nioteulcsed ni ND.A

hiWt boiiinhnti fo ,TS an ibaaelncm of iceotolsdenyuedx dna cendsarei lvlees fo MPdU eri.as htoB uesca DNA gae.dam

WI()KI

link981  Just look at page 36 of FA 2018 and memorize that shitty diagram o De novo pyrimidine and purine synthesis they ask so much about. No need for scientific explanations for this one unless you like to waste time. +20