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NBME 22 Answers

nbme22/Block 2/Question#25 (39.1 difficulty score)
A 37-year-old woman undergoes excision of a ...
AngiogenesisπŸ”
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 +6 
submitted by armymed88(47),
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john055  it looks like the patient has new onset erythema which points to infection and I think neutrophils make sense. I myself have marked angiogenesis but I did it offline. Is angiogenesis the right answer ? +1  
almondbreeze  yup +  
almondbreeze  according to FA 2019 pg217, neutrophil is present during inflammatory phase- i.e. only up to 3d after the wound. After that we have the proliferative phase with granulation tiss. and angiogenesis, epithelial cell proliferation, dissolution of clot, and wound contraction (involved cells: fibroblasts, myofibroblasts, endothelial cells, keratinocytes, mf) +  
mitchell_to_lakers  why not fibrosis? +  
waterloo  mitchell_to_lakers They are asking why is the incision erythematous and slightly warm. When someone is red, Dr. Sattar says that's because blood is going there. Fibrosis isn't a mechanism where someone's tissue will appear red and warm, it's collagen deposition. +4  
juanca10  Very good! +  



 +2 
submitted by btl_nyc(54),
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 +1 
submitted by asharm10(20),

It,s not an infection, it's basically a healing process, angiogenesis leads to warmth and erythema,

pfebo  It says no pain or drainage on the stem, this is how I eliminated the answer choices of infiltratiom (neutrophil, lymphocyte) +