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NBME 22 Answers

nbme22/Block 2/Question#47

A 22-year-old woman who is at 16 weeks' gestation ...

Down syndrome

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submitted by armymed88(13),

Down syndrome 2nd trimester screen (usually around 16-18wks) shows decreased AFP, estriol and increased hCG and inhibin A.

Of trisomy 13/18/21, Down Syndrome is the only to have an eleveted hCG