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Retired NBME 23 Answers

nbme23/Block 2/Question#18 (reveal difficulty score)
A 48-year-old man comes to the physician ...
Perforated peptic ulcer ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—imnotarobotbut(184)
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The key is the free air in the abdominal cavity. Ulcers, especially duodenal ulcers, can perforate into the abdominal cavity. This can cause a pneumoperitoneum (free air under the diaphragm). Not a listed symptom in this question, but this can also cause referred pain to the shoulder by irritating the phrenic nerve. FA 2019 pg 374

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et-tu-bromocriptine  To add on to this, anterior* duodenal ulcers tend to perforate (makes sense because closest to the abdominal cavity) whereas posterior duodenal ulcers tend to bleed (due to proximity to the gastroduodenal artery). +15
smc213  Acute pancreatitis can also occur with a posterior duodenal ulcer rupture. Source: Pathoma +6
victor_abdullatif  Fun fact: anterior duodenal perforation are more common than posterior because of the physics of the flow of chyme from the stomach into the duodenum. It travels in a manner that hits the anterior portion of the duodenum, therefore leading to ulcer / perforation. +2



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