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lispectedwumbologist
That's so infuriating I stared at this question for 20 minutes thinking I did something wrong
+76

seagull
lol..my math never worked either. I also just chose the closest number. also, screw this question author for doing that.
+9

yotsubato
Why the FUCK did they not just give us a clearance of 0.1 if they're going to fuckin round it anyways...
+18

cr
in ur maths, why did u put 24h/1day and not 1day/24h? if the given Cl was 0.09L/hr/kg. I know it just is a math question, but iΒ΄d appreciate if someone could explain it.
+1

hyperfukus
magic math!!!!! how TF r we supposed to know when they round and when they don't like wtf im so pissed someone please tell me step isn't like this...with such precise decimal answers and a calculator fxn you would assume they wanted an actual answer!
+1

jean_young2019
OMG, I've got the 25.92 mg/kg/day, which isn't any of the answer choices listed. So I chose the D 51.8, because 51.8 is double of 25.9......I thought I must have make a mistake during the calculation ......
+6

atbangura
They purposely did that so if you made a mistake with your conversion like I did, you might end up with 2.5 which was one of the answer choices. SMH
+5

titanesxvi
I did well, but I thought that my mistake was something to do with the conversion and end up choosing 2.5 because it is similar to 25.92
+3

makinallkindzofgainz
The fact that we pay these people 60 dollars a pop for poorly formatted and written exams boggles my mind, and yet here I am, about to buy Form 24
+20

qball
Me after plugging in the right numbers and not rounding down : https://i.kym-cdn.com/entries/icons/original/000/028/539/DyqSKoaX4AATc2G.jpg
+1

frustratedllama
Not only do you feel like you're doing sth wrong but then that feeling stays for other questions. sucks so baad
+

fexx
'here.. take 50mg of vyvanse.. I just rounded it up from 30.. dw you'll be fine' (totally doing this with my patients 8-))
+1

cbreland
I was so close to picking 2.5 because I thought I did a conversion error. 5 minutes later and still didn't feel comfortable picking 28.8π‘
+

yesa
12ug/ml = 12mg/L; 12mg/L x .1L/hr/kg x 24hr/day = 28.8. No need to multiple numerators and denominators by 1000s
+

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tyrionwill
When I got 25.9 and found nothing exactly matched, I guessed that the maintenance dose might be a bit more due to the bioavailability. So this antibiotic probably was not an I.V. formula, but an oral one, with a roughly 90% BA.
+2

eradionova
Well then it could have been equally likely that it had a 50% BA and the answer would be 51.8 exactly. I almost considered picking that but in the end stuck with the one that was closest to my answer lol
+2

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In the question they also don't say whether the antibiotic is administered IV or orally. For an IV dose, F = 100%. For an oral dose, F is typically <100% (FA 2019 p. 233). Based on this, IV maintenance dose would be 25.92 mg/kg/day. However, it is *possible* that the antibiotic is being given orally and F is closer to 90% (just an example). If this is true, the maintenance dose would be 25.92/0.90 = 28.8. This is obviously based on assumptions, but hopefully another way to explain why the answer is not exactly 25.92.

veryhungrycaterpillar
Oral antibiotics for septicemia? None of the Step 1 question writers are medical doctors, so this actually makes sense.
+1

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faus305
Don't skip it but flag it, give yourself 1 minute and 30 seconds or less to figure it out and if you don't then move on and come back if you have time.
Questions like these are what I like to call "time wasters." I got it wrong because I selected 2.5 assuming I made a conversion error when I arrived at 25.9 as my answer.
I think the lesson to learn here is that 28 is closer to 25 than 2.5 and NBME are evil people that know I'm not gonna make a conversion error. If you do math in a question and you are SURE you did it write, select the answer closest to the answer your math got you.
+

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1g2m=mlLg/12M/ 2
1*..000=198 k1/r/h0.m
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mousie
Equation is Maintenance dose = (concentration at steady state) * (Clearance)
if you convert all the units to what it wanted them in (mg/kg/day) you'll get 25.92 like weird-in said above
I didn't think to round 0.09 to 0.1 of course so I guessed 2.5 assuming I must have done a conversion wrong and was off by a tenth .... BOO bad Q
+4

submitted by wired-in(67), 2019-05-30T03:40:03Z

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