Clodipogrel prevents platelet aggregation by blocking the ADP receptor. The ADP receptor is what is responsible for putting GpIIb/IIIa receptors on the surface of platelets. Without GpIIb/IIIa, the platelets cannot aggregate together.
paulkarrJust adding that Clopidogrel irreversibly inhibits the P2Y12 receptor. This can be found in FA2019, pg 403. The other drugs in this category are: Prasugrel, ticagrelor, and ticlopidine. Ticlopidine is famous for causing Neutropenia and having an increased risk for TTP.+4
submitted by โimnotarobotbut(184)
Clodipogrel prevents platelet aggregation by blocking the ADP receptor. The ADP receptor is what is responsible for putting GpIIb/IIIa receptors on the surface of platelets. Without GpIIb/IIIa, the platelets cannot aggregate together.