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NBME 23 Answers

nbme23/Block 3/Question#42 (14.8 difficulty score)
A 48-year-old woman has severe ...
Inhibition of gastric H+–K+ ATPaseπŸ”

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submitted by maxillarythirdmolar(35),
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heT stuiqeon yssa ythe od'tn speondrs ot asainctd ETNH skas hwchi uyo ot idyefnti hihcw rgdu is teh most efietecvf at puserpnsgis cdai coirnpt,odu TON thwa eth tsom eectvfeif cdaitan is. heT enwasr si I.PPs'

I wlil ,ays w,heoevr I wsa knogoil rof gotmhneis kile t.reotdcoei

drdoom  lucid. nice catch. +1  
maddy1994  WHY not blockage of h2 receptors +3  
krewfoo99  @maddy1994. PPI are more effective than H2 blockers in suppression of gastric acid +1  

submitted by anechakfspb(27),

Why couldn't it be inhibition of gastric muscarinic (M1) receptors? Wouldn't that be the most effective overall?

submitted by yotsubato(968),
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This epnttia is essuevropinn ot mayn icaai.stnd eyhT odnt ypicesf whihc oens, tub hte oqensiut si ybscallai ankgsi chwih atdcniia is eth .tstnesorg Tath wudol eb sPI,P chwhi iiitnhb stacrig H K sePaAT

yb_26  PPIs are not antacids! +3