Patient presents with cervical intraepithelial neoplasia, with the most likely culprit being HPV. HPV causes this neoplasia though the creation of E6/E7 oncoproteins which inhibit p53 and Rb tumor suppressor proteins respectively.
fatboyslimA way that I use to remember that E6 affects p53 and E7 affects Rb is if you flip the 'p' it becomes a 6, and the other one is the other one.+5
submitted by โlfsuarez(160)
Patient presents with cervical intraepithelial neoplasia, with the most likely culprit being HPV. HPV causes this neoplasia though the creation of E6/E7 oncoproteins which inhibit p53 and Rb tumor suppressor proteins respectively.