NBME 24 One in four will have 25% β-globin function and may require occasional transfusions (NBME Answers)

Retired NBME 24 Answers

nbme24/Block 1/Question#40 (reveal difficulty score)
A 26-year-old man and his 25-year-old wife ...
One in four will have 25% β-globin function and may require occasional transfusions 🔍 / 📺 / 🌳 / 📖
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+31 upvote downvote
submitted by ∗brethren_md(105)

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aekM a utpentn qusear twhi a socrs fo B +B dna B 0;B B+ tpesrersne %05 futioncn leihw B0 epeserstnr 0% (nul)l iucotf.nn oS ni tihs ce,as eth hanudsb wluod eahv a B B0 ypngtoee lhwei teh eifw has a B +B neyetpog.

rsCso fo etesh tow illw sutrle ni eth fonllogwi n;egesypot ,BB B,B0 +B,B +BB0 B B = 001% fit,connu +BB = 75% icn,foutn 0BB = 50% ion,futcn +B0B = 5%2 cnitnouf

oS teh rseanw illw eb 1 in 4 ehva a 25% nfoinuct gevin eth .petgnsyoe

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tyrionwill hwo otuab het icchoe of :D 1 ni 4 have 05% ntf,unoic iwchh si ru.te lsalh 5%0 oncinuft nesed trofunsnsai? +

tyrionwill nI F,A it nfsedie ebat smasilheaat toni irmno bA2(H )&5.t;3%g adn ojamr t(ohb HFb adn 2bHA og ehfrurt )u,p dan the mjaro dsnee nsforsatuni lryu.efnetq oHw anc ew keat sith ificocntsaalsi edsba opun qniuietvat wya kile in this oin?teuqs ohw mcuh eptenarcge fo tonfuinc felt sdoe tno ende a euqnetrf ussnoritfan? +

azibird D ssay noe ni OW,T ont eon ni .UFOR +6

hemehero Is hteer a ayw to wnko thta B0B+ wlil = 52% u.ncionft I wsa ctuks bentwee 52% fnncuito dan 01% ouincfnt, but dcolu'tn fergui tou who ot esorna enteebw het wto fo .emht +3

neil_simmons Teh utiesqon assy het hteorm sha a tnmatoui woknn ot ecasu 50% seaderce in an-beoitgbl eneg nnfucoti fo eon lel.ael oS if one eallel is ikrowng at %05 +B() nad eth eotrh eelall is rignkwo at %0 0B,() htne atht wudlo amen taht crplariaut ste fo leellsa lwduo noitncuf ta 2%5. +2

twich22 Teh yKe rhee is teh nmoaw ash %05 seecerad ni cnifount "Of eon "ealll.e tIs a tpudsi awy ot owdr ti, tBu ti aesnm htat noe aellle krswo ta 5%,0 chiwh lwodu be B.+ oS if oyu vahe a +B0/B srffogi,np eht B0 veigs %0 adn het B+ worsk at %50 aip,tcayc so uyo yonl eavh 2%5 of l.marno +

murad smeo oen laxiepn tsih to em eaelsp, hwo meco fi eth tmhoer twhi hsi neopeytg +BB has %50 nntfiuoc of neo lleae.l iwehl fi ew teg ehr ofrsipnfg pntenu reqaus we srodncie teh one htta hsa teh aems nteogeyp sa hre BB+ fo vinahg %57 nt?oun?cif +

+3 upvote downvote
submitted by ∗an_improved_me(91)

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I leef ielk tis tsehe sikdn of ssuinoqet tath lrelay keam a skeat-ettr sde.ecuc You dlouc hvae uietdds yuor eolhw lfie fro tSep ,1 and eemnh.co.t. pu nasitag a nieoutqs keli ist.h sIt ttigsne posctnce hatt yr'ueo iiralfma wthi .e.(g asetat-al,Bemashi g),eitnces utb ni a wya hatt sint' ntosiehgm 'dyuo erve yeitcdrl .nelar uY o vhae ot sayt ,cmal anylzae wtah you nko,w thaw eht osiqnuet is ikg,sna ertcea a tyrsgaet ot e,rswan nda okol ta chhwi wnaers si e.sbt

I veyn emso of !yuo!

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+1 upvote downvote
submitted by ∗medstruggle(21)

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tWsha the fnrefecdie bteenew tozurh“eoegsy nllu oaminttu ni B goblni e”neg adn erzoget“suhoy uoaitmnt wonkn to caues %50 aseeedrc in B blinog nege uocnfnti fo neo ”ll?alee

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welpdedelp I pinrteeertd ""lnul sa geimann ullf oedenlti eiwhl het hreot etusogozehyr mntsuitoa was noyl a %50 ecesaedr in teh fnci.nuto eOn dhcil uwodl therini 1 ulln amtioutn nda 1 %05 amiotu,tn iwchh wludo vlaee ethm htwi a 5%2 fuaitnlcon .eeng +18

j44n A alth is hte dtenelio, B tlah is uonsmaitt no rretmspoo or plseci .sseti +

-1 upvote downvote
submitted by mynamejeff(0)

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I nitkh E is loas .ea..livb 1/4 is /BB nad eaorhtn 14/ is B/B+ . The +BB/ is -eshtiBmalsaa orinm ewhre B ahinc si ecdprudndoure isnuftno(c rao)lmynl and si lyuslau yt,camomtisap epr FA 02(20 gp. 4.1)8

u?hTsgtho

so,Al my tdsndnrengiau no asiBmast-ahle mfor D.r tStara and tsfir iad is thta ti's nto tes in tesno htat B+ si %50 uidc.optrno It esmse ot yr.va

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syringomyelia1 E yass /12 nto 4/1 +1

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