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Retired NBME 24 Answers

nbme24/Block 3/Question#42 (reveal difficulty score)
Which of the following terms best describes ...
Lamins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem cell_bio extracellular_matrix

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 +73  upvote downvote
submitted by โˆ—atstillisafraud(217)
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I like this question because it reminds me that examiners think objects can exist in 2 dimensions.

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ghrelin  It's only a matter of time before we, too, lose our thickness and fall into their grid. +1



 +19  upvote downvote
submitted by โˆ—tea-cats-biscuits(273)
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Fibronectin is an extracellular matrix glycoprotein, while lamin is an intermediate filament that specifically provides support to the cell nucleus. Donโ€™t confuse lamin with laminin (science hates us clearly); laminin is like fibronectin, an ECM glycoprotein and a major component of the basal lamina of basement membranes.

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masonkingcobra  Lamin looks like a "cross" and held up Jesus and the basal lamina is super important just like jesus (you bet there are people who believe this) https://answersingenesis.org/biology/microbiology/laminin-and-the-cross/ +45
dr.xx  blasphemy @masonkingcobra +1
luciana  I clearly confused lamin with laminin, now I know +3
almondbreeze  FA 2019 pg 48 lamin +1
almondbreeze  picked tubulin but i guess tubulin makes up microtubules and therefore is spherical +
abkapoor  Also remember progeria is due to lamin a dysfunction, and progeria patients have messed up nuclei +
brise  @abkapoor the f is progeria? and do we need to know it for step? +
brise  @abkapoor omg jk jk wow +



 +5  upvote downvote
submitted by โˆ—nwinkelmann(366)
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So... I didn't know what it was so I looked it up... and legit, granum is part of plants.......... really?! lol

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cinnapie  We out here treating plants!! +8



 +5  upvote downvote
submitted by โˆ—sweetmed(157)
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Lamins form a nuclear membrane surrounding DNA. imp for structural support, organizing genome, regulating gene transcription. Defective in Progeria and muscular dystrophy.

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 +4  upvote downvote
submitted by โˆ—apurva(101)
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I think for nbme 24, i wasted my hard earned 60 usd

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 +3  upvote downvote
submitted by โˆ—b1ackcoffee(115)
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Any good material to prepare for this kind of stuffs?

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apurva  Lord Jesus +14
ozmartini  Had to think back to my cell bio class in undergrad +



 +0  upvote downvote
submitted by sunny(9)
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https://www.google.com/search?q=LAMIN&tbm=isch&q:lamin,g_1:nuclear+envelope

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 -4  upvote downvote
submitted by โˆ—soph(84)
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"Nuclear laminin dissasembles + reform nuclear envelope during mitosis. They are helpfull for structure and transcriptional regulation in cell nucleus." -OSMOSIS

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 -5  upvote downvote
submitted by โˆ—soph(84)
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"Nuclear laminin dissasembles + reform nuclear envelope during mitosis. They are helpfull for structure and transcriptional regulation in cell nucleus." -OSMOSIS

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