rihanBetween the glomerulus and Bowman's space there is a hydrostatic pressure gradient.
This gradient is normally the result of a LARGE glomerular hydrostatic pressure and a LOW pressure in Bowman's space which normally favors filtration.
Diagram here: http://physiologyplus.com/wp-content/uploads/2017/08/Glomerular-Filtration.png
In the case of post-renal obstruction, hydrostatic pressure behind the blockade will rise and urine will reflux into the capsular space and renal tubules (while glomerular hydrostatic pressure is unaffected) effectively decreasing the pressure gradient which reduces the filtration rate.+12019-07-04T19:42:54Z
trichotillomaniacthe key here is the term hydronephrotic kidney. anytime there is that, there is a post renal obstruction of some sort. The fact that he has progressive renal failure just contributes to the idea that his kidneys have seen damage before and are not able to withstand the pressure from the back up as well. I got tripped up on this. The important thing to note is that Hydronephrosis and dilation = back up = increased in volume pressure (hydrostatic) +12019-06-24T18:41:28Z
for every thousand thrashing at the branches of evil there is one hacking at root