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NBME 24 Answers

nbme24/Block 3/Question#37 (reveal difficulty score)
A man accidentally touches the surface of a ...
Interendothelial gaps in venules ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: derm pathoma

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 +12  upvote downvote
submitted by โˆ—sympathetikey(1599)

As per Pathoma,

"Vascular permeability occurs at the post-capillary venule"

This is why, when you have edema, you would have gaps in the venules.

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j44n  that was my exact reasoning +3



 +6  upvote downvote
submitted by โˆ—seagull(1933)

โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–ˆโ–€โ–€โ–‘โ–‘โ–ˆโ–‘โ–‘โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–„โ–€โ–€โ–€โ–€โ–‘โ–‘โ–‘โ–‘โ–‘โ–ˆโ–„โ–„โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–ˆโ–‘โ–ˆโ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–โ–โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–„โ–‘โ–โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–ˆโ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–„โ–€โ–€โ–‘โ–โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–‘โ–„โ–€โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–โ–‘โ–„โ–„โ–€โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–„โ–€โ–‘โ–‘โ–‘โ–โ–‘โ–‘โ–‘โ–‘โ–‘โ–ˆโ–„โ–€โ–‘โ–โ–‘โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–ˆโ–‘โ–‘โ–‘โ–โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–„โ–‘โ–ˆโ–‘โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–ˆโ–„โ–‘โ–‘โ–€โ–„โ–‘โ–‘โ–‘โ–‘โ–„โ–€โ–โ–‘โ–ˆโ–‘โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–ˆโ–โ–€โ–€โ–€โ–‘โ–€โ–€โ–€โ–€โ–‘โ–‘โ–โ–‘โ–ˆโ–‘โ–‘โ–‘โ–‘โ–‘ โ–‘โ–‘โ–โ–ˆโ–โ–„โ–‘โ–‘โ–€โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–โ–‘โ–ˆโ–„โ–„โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–€โ–€โ–„โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–„โ–โ–„โ–„โ–„โ–€โ–‘โ–‘โ–‘ โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘โ–‘

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paanvaannd  lollll this doesn't exactly come through on desktop but it sure is funny on a mobile browser. +5



 +3  upvote downvote
submitted by โˆ—guillo12(57)

In situation of an inflammatory response such as in burns, anaphylaxis or sepsis, intercellular contacts disintegrate in post-capillary venules leading to intercellular gap formation.

https://www.ncbi.nlm.nih.gov/pubmed/28231640

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 +0  upvote downvote
submitted by jucapami(14)

https://www.ncbi.nlm.nih.gov/pubmed/6162412

"The morphological interpretations of the changes in the functional ultrastructure of the bloodlymph barrier following thermal injury seem to be an increase in the numbers of vacuoles and many open endothelial intercellular junctions..."

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 +0  upvote downvote
submitted by cr(5)

Which type of cell we r going to find in blisters?, neutrophils?

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thotcandy  acute inflammation so i assume neutrophils to be replaced by macrophages -> granulation tissue -> fibrosis/scar formation +



 +0  upvote downvote
submitted by โˆ—an1(114)

UW: "gaps between endothelial cells allow blisters to form". this guy has a blister.

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