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Retired NBME 21 Answers

nbme21/Block 4/Question#31 (reveal difficulty score)
A 48-year-old woman comes to the physician ...
Paracrine stimulation of osteoclasts by osteoblasts ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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pg32  ePdcki D eipesdt tegrndsidnuan eht aevbo ^^ sebueac I-1L si slao wnnko sa tesoslocat iittanviagc ..tofarc. +8
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caitlyncloy  h..o ti eesm ARKN L si eeecdrst to aceattiv teh .lsc.sta i aws pguntriic ti sa NLARK saw on the fcauers of the tbas.l ferceen: er .chevweIhbwtJhtwt=mwuBR?/ec/op.O/attsAy:suo +1
makingstrides  fI you acn, I Wlodu ighlhy ernemdocm nlgooik at the hyctkse arpmh rof h.sti It asnpeixl hits elw,l in ym oninpio, dna ilynfideet hdlepe .me +
jatsyuk38  anjolG I uevo'cld rnows dias HTP tasietlmus astlsbotoes ot tscreee L-1I to tactaeiv tslcoose.ast eH alos dias rotengse rsetnvpe issootsopore by bhitingini ateslsootb alseeer of .Ivhre.oL-ew1. htere is olsa a doWUrl oeustqni erhew ti adis LKA-NR asylp a orme mpiartnto roel tacor e(vor )L1-I ni TPH dtiemdea enob wboednkra +1

Primary hyperparathyroidism: overproduction of PTH by parathyroid chief cells Effect of PTH on bone โ†’ increased bone resorption โ†’ โ†‘ release of calcium phosphate โ†’ โ†‘ calcium levels Induces RANKL expression in osteoblasts โ†’ binding of RANKL to RANK on osteoclasts โ†’ activation of osteoclasts Induces IL-1 expression in osteoblasts โ†’ activation of osteoclasts" Amboss

Not sure why D is wrong

+/- alexv0815(10)

Primary hyperparathyroidism: overproduction of PTH by parathyroid chief cells Effect of PTH on bone โ†’ increased bone resorption โ†’ โ†‘ release of calcium phosphate โ†’ โ†‘ calcium levels

Induces RANKL expression in osteoblasts โ†’ binding of RANKL to RANK on osteoclasts โ†’ activation of osteoclasts

Induces IL-1 expression in osteoblasts โ†’ activation of osteoclasts

Not sure why D is wrong

+6/- alexv0815(10)

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