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NBME 22 Answers

nbme22/Block 1/Question#12 (16.8 difficulty score)
During the first week of life, a male newborn ...
21-Hydroxylase🔍
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 +2 
submitted by wutuwantbruv(26),
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 +0 
submitted by dr.xx(143),
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iegnonCatl adrnael ihlrpspeyaa ued to 1e-yhs2rolxayd dfceiincey.

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wutuwantbruv  Can't be 17α-hydroxylase because this would present with hypertension and some sort of ambiguous sexual presentation (males) or lack of secondary sexual development (females). Can't be 11β-hydroxylase because this would present with the opposite of the kid's presentation due to the production of 11-deoxycorticosterone (similar effects to aldosterone but not nearly as potent). The other two would not really make sense since there are increased levels of 17-hydroxyprogesterone. +