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NBME 22 Answers

nbme22/Block 1/Question#25 (46.8 difficulty score)
During an experiment, a 22-year-old man ...
Arteriolar resistance: decreased;
Capillary hydrostatic pressure: increased;
Capillary filtration rate: increased


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submitted by its_raining_jimbos(21),
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tNo 0%10 resu no htis ,noe tub erh’se ohw I dahppcaroe ti: hastmeini aucess ilratare aoitldin ead=(ecsrde irraotrale ecsaesn)i,tr utb lal of hatt loodb ahs ot go esoehermw cesni uyo now avhe moer oblod lfigonw hgrothu hte rtiraees adn thta srheoemew si het rpesaalilic rdciesane( cylraipal oaidrtthsyc )psr.esure itenaHsmi esausc dieeracns lebeiiratypm fo hte llpcipta-yrsao veesnul (noe fo rD. a’Statrs tveorfia fcat)s os uyo’d haev risdneaec iypclraal tfaintirlo .raet

taediggity  Totally agree, arterial dilation--> increases blood flow into capillaries/increases capillary hydrostatic pressure + increasing permeability of the post-capillary venules= Increased Capillary Filtration Rate +1  
makinallkindzofgainz  I love you explanation, but I don't think filtration rate is dependent upon permeability of the post-capillary venules. I think the filtration rate is increased simply due to the increased blood flow; this is similar to how increased renal blood flow will increase Glomerular Filtration Rate (GFR). +10  

submitted by link981(156),
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etHmsinai usscae oleerirta oivisa,onadlt sucgnai a pbludui fo boldo ni teh The ecsaenrdi odolb in eht aileirsplca lwli csuea eht resrpeus etreh ot ries. toilFntira si nneedptde no u,seesrrp eth rihgeh eth rsep,seru het omre teh itofrtlin.a

eeebmmRr oolbd lf:wo nives to evsueln ot csiaalelirp ot tsolrieaer to tsaerrie

yb_26  agree in all, except the blood flow - it is right the opposite [] +13  
link981  I stand corrected @yb_26. Brainfart moment 🙈 +  
rockodude  lmao including a link to a teachmeanatomy page on basic blood flow +  

submitted by moneysacs(1),
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itmeansHi ascsue a aeescedr ni ycrthoatsdi rurpssee get( ,tish ist’ a odtvliaras)o tbu tneh ucesas an cineesar in yclaplira adyiohcsrtt essrrep?u aOk,(y ihst si hwo it usscea emade, I guse.)s Deos yoanen tge woh tihs yatlulca w?skor

its_raining_jimbos  Not 100% sure on this one, but here’s how I approached it: histamine causes arterial dilation (decreased arteriolar resistance), but all of that blood has to go somewhere since you now have more blood flowing through the arteries and that somewhere is the capillaries (increased capillary hydrostatic pressure). Histamine causes increased permeability of the post-capillary venules (one of Dr. Sattar’s favorite facts) so you’d have increased capillary filtration rate. +  

submitted by alexb(46),
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Whta teyh mane yb tia.f.on.itlr

ilduF cmdiesrop of eatrw dna eo,ettlcerlsy hwit a yvre mllsa aotumn of peoirnt dan trheo l,roumcacslmeeo lnamrloy esalve lrialepicsa nda asllm ypriltloaspca neeslvu by a pecossr cealdl irattlio.fn iittlnraoF si ylrrmiaip vrnied by the caypirall chiotsryatd rp,sseeru dna the ounmat rldtfiee erp niut emti is ylindadoaitl nuedfeclin by eht aieepyrtblmi fo hte veless lwal e(minudhotle dan seatebnm .emmnea)br The ufild atth istrlfe tnoi eth uiesst ofswl tiwinh eht ielacurlnlter ecpas he(t ttiuinteims)r dna mtos of ti is dsrrbeeboa ta eht rnauelv dne fo esriillcpaa hweer eht dryhitcsato ersrespu si ewro.l oSme fo teh deirtfle iludf is nktae up yb yiptmahcl sslesve nad teunerdr to het ic.rotnlcaiu

submitted by azibird(158),

Histamine decreases arteriolar resistance, but I guess not capillary resistance.

ΔP = Q × R

In the arteriole, resistance decreases, so flow increases. In the capillary, resistance has not decreased, so the increased flow they receive translates to increased pressure and filtration.

submitted by atstillisafraud(187),
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sHntaemii suseca yirapcall errlritaoa ntioladi cser(aeed nnt)cceraesi(iresased epressur ni eht caayrlpil ceasebu frftseeen imnare eth seam sz)ei tsHmiaien sola aisnsreec larplaciy metipabiyrel.