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NBME 22 Answers

nbme22/Block 3/Question#40 (31.0 difficulty score)
A 49-year-old man has had the gradual onset ...
Essential thrombocythemiaπŸ”
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 +11 
submitted by link981(156),
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reP stiFr iAd 0128 (gp 2)14 &p;ma Mcerk lanuMa

a) MLC si not eht awrens baeesuc in LMC yuo avhe HIHG WCBs a∓ sPe.aetltl In teh tsme rteeh si olyn ghih ta.p)btlseel Is eth awrsen cseeaub ni eEatssiln ayhbTimoemhtcro ew aevh malrno WCBs and sRBC, usjt gihh la )eepct.stl dMeiloy maaasltepi esferr to elwl a amltsieaap ni olyimed ecsll wchhi rae oh,lbssipa phlsoenois,i e.t) dc nI iheomltayPcy eaVr ew aehv IGHH ,RCBs CsBW, dna lPts et)aele. tRiaevec hoyoorimt-bscts is a leetaved elttapel tucon thta scrocu ayendsrco to enotarh soidrdre lei:k

hn-oricC ialoytmnrafm eidrsdors (eg, detumoairh i,rithsrat roainytmlafm ebwol ssiee,ad elbrcus,isuto idoacsssir,o oiussnmrtaloga ihtw puc) -eiitgilsanoyAt cefoiitnn

ohrraHemg-e

no-rI nicfedieyc

yoeisH-mls

Cnr-eac

-cmeSoyelnpt ro lpsesonmiphy

impostersyndromel1000  perfect response right here +  
paloma  Essential thrombocythemia presents with platelets > 1 million, not reactive thrombocytosis +  



 +2 
submitted by bubbles(66),
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Tkea a olko ta ttah iveamss teleatpl ocntu -- eorv a omliiln epr m3m! thTa lsuohd onpti uyo trsawdo a aemrplrivilooeyfet sdoerrdi of emso tros cnsie tish lalef s'tin ibednelg uot sa fra as ew acn llet mofr teh oobld aplen (cwhih uodwl ptu ciartvee rsiytchbtsomoo on eht )x.dd

wNo lset' okol ta etsoh y.eeoshrttrcy lomaNr -- os ti's nto matyhciepoly a,rev and oeidcrsignn teh calk of setikloo,ucys oalrybbp nto LMC or ydmioel sipmealata.

oS oru rawnes stmu be tnsislaee imoymrehhbo!attc




 +2 
submitted by lola915(34),

Just want to add that the pale, blue mottled finger is a symptom of essential thrombocythemia called erythromelalgia. Also a symptom in Polycythemia Vera but this dudes erythrocyte count is normal.




 +1 
submitted by haliburton(208),
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FA 7:021 rdacherzteaCi by msiesva pinroaetoirlf fo ysteoyrakemagc nad la.seettlp yomsmSpt dieulcn gneeilbd nda t.mssibhoro olBdo aersm shosw drmyleak eescnardi ruenmb of estlelpat, which may eb eaglr or rsewoihet oyllnmraab mefr.od gltylmraeioharE aym .rcouc




 +1 
submitted by djinn(5),

Essential thromcythemia is a neoplastic proliferation of mature myeloid cells, especially platelets.

High neutrophils and eosinophils