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NBME 22 Answers

nbme22/Block 4/Question#2

Thirty minutes after taking 2 aspirin tablets for a ...

Acetaminophen

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submitted by generic_login(7),

This is aspirin-intolerant asthma. Acetaminophen only inhibits COX within the CNS, so doesn’t cause the leukotriene shunting that characterizes that disease.





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submitted by gainsgutsglory(4),

Why is acetaminophen the correct answer other than process of elimination. NSAIDs can be used for tension HA and she’s too old for Reye Syndrome (i mean technically shes a child since shes <17, but not a classic picture at all). I’m confused.

zelderonmorningstar  My reasoning was that aspirin and the other 3 are all NSAIDs, and she had an adverse reaction. Acetaminophen is not an NSAID, so she probably won’t have the reaction. +  
gainsgutsglory  @zelderon But what’s the pathophys here? +  
generic_login  This is aspirin-intolerant asthma. Acetaminophen only inhibits COX within the CNS, so doesn't cause the leukotriene shunting that characterizes that disease. +2