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NBME 22 Answers

nbme22/Block 4/Question#29

A 45-year-old man who is HIV positive comes to the ...

Disruption of the pathogen cell membrane

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submitted by haliburton(74),

pathogen: cryptococcus

Treatment options: Ampho B: binds ergosterol -> pores in fungal membrane -> leaks contents. can add Flucytosine: converted to 5-FU to inhibit nucleic acid synthesis

https://step1.medbullets.com/microbiology/104161/flucytosine https://step1.medbullets.com/microbiology/104158/amphotericin-b