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NBME 23 Answers

nbme23/Block 1/Question#8 (23.8 difficulty score)
A 30-year-old man with HIV infection comes to ...
It increases plasma concentrations of other PIs also metabolized by cytochrome P450🔍
tags: biochem p450 pharm drug_interactions 

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submitted by step420(33),
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mousie  who knew +1  
sympathetikey  Right on (thanks sketchy) +6  
mguan1993  MAGIC RACKS is a good mnemonic ive heard for 450 inhibitors (macrolides, amiodarone, grapefruit, cimetidine, RITONAVIR, alcohol (chronic), cipro, ketoconazole, sulfa +3  
criovoly  "CRACK AMIGOS" Cimetidine Ritonavir Amiodarone Ciprofloxacion Ketoconazole Acute alcoholism Macrolides Isoniasid Grapefruit juice Omeprazole Sulfonamides +5  
drzed  Macrolides EXCEPT azithromycin -- they like to trick you with that one. +1  
steatorrhea  chronic alcohol induces 450, acute alcohol inhibits 450 +