link981I think q should be 1/100. You got p and q mixed up.+4
humble_stationBecause p = 99/100, you can just make it 1. Then just do 2 x (1/100) and you get 1/50+6
humble_stationBecause p = 99/100, you can just make it 1. Then just do 2 x (1/100) and you get 1/50+2
unhappy_triadCarrier frequency= 2pq
AR disorder that occurs in 1 in 10,000 the square root of 10,000 is 100
so, q=1/100=0.01, p= a number close to 1, just use 1.
plug it in the equation 2pq= 2(1)(0.01)=0.02=1/50+6
submitted by โseagull(1933)
Hardy-Weinberg equation = 1= P^2 + 2pq + q^2
P^2 = 1/10,000 = 1/100
Then remember P + q = 1 ------> 1/100 + q = 1 (q = 99/100)
Lastly plug back into Hardy-Weinberg Equation as:
2pq = Heterozygote carrier
(2 x 1/100 x 99/100 = 2/100 = 1/50)