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Retired NBME 23 Answers

nbme23/Block 4/Question#11 (reveal difficulty score)
A 40-year-old man comes to the physician for ...
Finasteride ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +17  upvote downvote
submitted by โˆ—yotsubato(1208)
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Yeah sure, lets give the guy who wants to keep his dick working and be attractive towards women Finasteride and completely ruin his testosterone levels and give him a limp dick, man boobs, and decreased performance in sports.

Sometimes the NBME really just makes me ask Why?

Topical minoxidil would be way better but no they wont put that as a choice

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anjum  To clarify: the lack of DHT production caused by finasteride leads to gynecomastia and ED. The other options are synthetic androgens. Totally agree that this question goes against the benevolence vs. maleficence that we've been taught in medical school +1



 +11  upvote downvote
submitted by โˆ—sajaqua1(607)
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Male pattern baldness./androgenic alopecia is caused by the effects of dihydrotestosterone (DHT) on the skin of the scalp. Testosterone is converted by the enzyme 5-alpha-reductase into DHT. Finasterideis a 5-a-reductase inhibitor, and so blocks the production of DHT and can halt or even cause some reversal of make pattern baldness. However this same activity may also result in signficant sexual side effects including gynecomastia, erectile dysfunction, ejaculatory dysfunction, and decreased libido.

A) Danazol- a weak androgen with antiestrogenic effects, used in the treatment of endometriosis and fibrocystic breast disease. C) Methyltestosterone- synthetic T, it is used to supplement in testosterone deficiency, or in the treatment of some breast cancers. D) Oxandrolone- an anabolic steroid used to regain weight. E) Stanozolol- another anabolic steroid, with potential used for hereditary angioedema.

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sajaqua1  I am embarrassed by these typos. +3
drdoom  lol +



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