NBME 23 Normoblasts (NBME Answers)

Retired NBME 23 Answers

nbme23/Block 4/Question#31 (reveal difficulty score)
A 32-year-old man who lives at sea level ...
Normoblasts 🔍 / 📺 / 🌳 / 📖
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submitted by ∗thomasalterman(181)

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A normoblast is an immature RBC, so it's elevated in states of increased hematopoiesis.

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sympathetikey Don't mind me. Just sippin my dumb ass soda over here. +76

someduck3 The term "Normoblast" isn't even in first aid. +40

link981 NBME testing your knowledge of synonyms. Have to know 15 descriptive words of the same thing I guess. +25

tinydoc I wish they would stop making it so every other question I know the answer and I can't find it among the answer choices because they decided to use some medical thesaurus on us. +23

qball Metamyelocytes = Precursor to neutrophils Siderophages = hemosiderin-containing macrophage aka heart failure cells +14

llamastep1 Theres a UWorld question about Parvovirus B19 that mentions "giant pronormoblasts" that helped me make the connection +10

fexx I got it right but would it hurt them to put RBCs? Medicine is hard as it is. No need to make the exams more complicated. I doubt my pt is ever going to as me if his/ her normoblasts are going to increase if they go hiking in the mountains +7

mdmikek89 Even in you didn't know what Normoblast means, it cant be any of the other answers. TEST TAKIN' SKILLZ BROS +

nerdstewiegriffin I can guarantee you this Q was written by some sadistic PhD examiner +18

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submitted by ∗whoissaad(102)

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Several names are used for nucleated RBCs—erythroblast, normoblast, and megaloblast—with one minor variation in word sense. The name normoblast always refers to normal, healthy cells that are the immediate precursors of normal, healthy, mature (anucleate) RBCs. The name megaloblast always refers to abnormally developed precursors. Often the name erythroblast is used synonymously with normoblast.

From all the things they could test us on... :)

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abhishek021196 https://epomedicine.com/medical-students/erythropoiesis-simplified/ “PB PORE” Proerythroblast or Pronormoblast (Rubriblast) Basophilic normoblast (Macroblast or Early normoblast or rubricyte) Polychromatic normoblast (Intermediate normoblast) Orthochromatic normoblast (Normoblast or Late normoblast or metarubricyte) Reticulocyte (Polychromatic erythrocyte) Erythrocyte erythropoiesis Remember the duration of erythropoiesis from proerythroblast to erythrocyte is 6-8 days (average 7 days). Proerythroblast to Reticulocyte = 4 days (1 day for each) Reticulocyte to erythrocyte = 2 to 4 days (reticulocyte spends 1-2 days in marrow and circulates for 1-2 days in peripheral blood before maturing to erythrocyte) As the cell matures the following morphological changes take place progressively: Cell Size: Decreases; Nucleus: Size decreases; Cytoplasm: Shrinks; Cytoplasmic basophilia decreases; Cell no.: mature cells increase and nucleated cells decrease +

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submitted by ∗daplatesofmetal(3)

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What is TARNATION is going on here!?

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