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NBME 24 Answers

nbme24/Block 1/Question#18

A 34-year-old woman with a long history of ...

Tuberculous osteomyelitis

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submitted by haliburton(75),

Infliximab is a TNF-alpha inhibitor. from pubmed TNF-α has been demonstrated to have a central role in the host response against tuberculosis, including granuloma formation and the containment of disease (14,15). Notably, antibodies against TNF-α induced reactivation of tuberculosis

bigjimbo  TB can spread to psoas L1-2 often, which then goes to the actual L1-L2 vertebrae itself (Potts or osteomyelitis) +1