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NBME 24 Answers

nbme24/Block 3/Question#18

A 55-year-old man with alcoholism is brought to the ...

Competitive inhibitor

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submitted by m-ice(116),

Competitive inhibitors increase the Km of the substrate. The Km represents how easily a substrate can bind the active site, with a lower Km representing easy binding, and a higher Km meaning more difficult. If you add a competitive inhibitor, like ethanol in this case, it makes it more difficult for the methanol to bind the active site, because it must compete with the ethanol.


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submitted by mcl(167),

lolol so instead of using fomepizole they just gonna get him real drunk

johnson  yep - supposedly, ethanol is used when a hospital/facility doesn't have fomepizole. +