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nbme24/Block 3/Question#18 (22.9 difficulty score)
A 55-year-old man with alcoholism is brought ...
Competitive inhibitorπŸ”
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 +7 
submitted by mcl(586),
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ololl so daients fo nugis zleiofompe hyet jtsu nogna gte ihm rlae duknr

johnson  yep - supposedly, ethanol is used when a hospital/facility doesn't have fomepizole. +5  
usmlecrasherss  Drink vodka man , either way you're dying +  
drschmoctor  Or if you really wanna get drunk and have a warm place to sleep, drink a bunch of methanol in the waiting room of the ED, then let them pump you full of ethanol and keep you safe. +2  



 +3 
submitted by m-ice(326),
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iepeCitmotv iibnshorit caesreni the mK of het tbu.rsaets ehT mK sseernrpet hwo aelysi a turatsbse can dnib eth aceivt ts,ie whti a lroew mK ngntrieepesr easy dnbg,iin adn a ghiehr Km niganem mero citud.iffl If oyu dad a imectoipevt brhiition, kile oeahtnl in hsti e,cas ti smkae it more cfdilifut orf hte meatohln to bdni hte ivtcea ite,s abeesuc ti smut cpeoetm tihw eht alon.eth

deathbystep1  but how is ethanol a "inhibitor" of alcohol dehydrogenase? isnt the concept that both ethanol and methanol compete for the same binding site of alcohol dehydrogenase and hence ethanol displaces methanol preventing its metabolism? if ethanol were to be a inhibitor it would have to shut off the enzyme, which is does not. +  
krewfoo99  @deathbystep1 Competitive inhibitor simply means increasing concentration of a particular substrate will allow more binding of the substrate to the enzyme. Thus the substrate with the higher concentration will competitive inhibit the other substrate by binding to the enzyme. It dosent necessarily shut off the enzyme +3  



 +1 
submitted by j44n(42),

I hate these so much these questions give me MCAT PTSD




 +0 
submitted by madojo(163),
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hTe Km si srnevleyi edtlrae to the yiiftnfa of the nemzye orf tis rtebstsau os ni this esac ew awtn ot craeisne Km so htta the naiyitff fo hcpteai llcohao ddhagsyneeoer cdasseere for nlothema nda het hneolta cna enht tca sa a tceipivmeto nbiothiri yb nogremociv het naencnoocrtit of lotenamh tuhs tnrpnviege xiiyt.cto