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Retired NBME 21 Answers

nbme21/Block 4/Question#13 (reveal difficulty score)
A 4-month-old boy is diagnosed with a rare ...
Dilated rough endoplasmic reticulum ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem repeat

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 +5  upvote downvote
submitted by โˆ—sklawpirt(34)
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I ihtkn teh edia rhee is ypmsli that eon ohusld tkinh aotub herwe iecslsve ear omicgn frmo no trieh awy to teh golgi pmxl.oec

wo"T spets rfarodw dan neo espt bcka." aeclpcSfyil eth niuostqe amy eb gnirfeerr to a arer ccoiliraanaf ie.srodrd na raasesewsn of ahtt dsseiae is ont aeyrnecss. Wath si yecrassne si dgadtnsurnein eth irngoi rfmo rwehe eevcslsi are idrtfkeca ot eth glGoi prautasap.

PIOC nretpoi si eeddne ot tcao ecvelss rfom teh ERR ot sden to ilog.g T,ush hiwt a uioattmn ni atht pnori,et hte acpgdkea osentrip ttah sloudh belb ffo adn eb ntes to the l,goig eatndsi aemclctauu in the ERR and idelta .ti Thsu the r.nawse

002)ah(/dl:3Sdw/02owc67j4/0p.w2tcmg/-t1.s/2-pf.hfl991pe

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hayayah  .gp 74 no FA got hte dogo lia!susv +6
notadoctor  *OPCII rsiotenp ear neddee to taoc selviecs mofr eth ERR to oG.ilg wP"ICO(Io)T tsspe fawrdo;r In(OoCeP) epts tea crn Ad a"grkoeb. gose RER -> olgiG >- sSoosee/eystorcrLym eVlessic >- aPslma rmaebenm +27
titanesxvi  why otn aslml ylooe?msss +5
varunmehru  nad I tuoghth grlae sloyeomss due to kacl of mnzysee to regaded +1
samsam3711  hTe izse fo the omlsyoes is nto dcfeafte by eht reesnecp ro sbeacen fo ro,petin but tsi cfotninu is omemriscodp (eg. reitnop is ttneigg tkcus ni teh ER)R +2
fattyacid  I heop iths slphe to wmreehov aws tosl iekl lNeml u imaout:nt A utaontim a( gchnae) ni a gnee atth dsale ot sit ont bieng inrtrsdacbe tion RAN ardo/n nrttedasal toni a cftounainl rtopien pctdor.u orF e,maxple a lunl outatnim in a eegn htta sauyull dcsenoe a iiescfpc zeemny daesl ot the utocndpior fo a ncutofnanniol mzenye or on znyeem at .lla +3
pingra  I khint ouy dmae a ypto: OICIP ERR( -;t&g cgliosi)G-; POIC tsi-l(grogan -> sl-ociigg dna igo-licsg &-tg; ERR,) lahtnicr ioctsesdy(no dan sol-rgigatn -> els)yooms +2
kevin  So ym tothhug rsepcso aws if terhe is on PCO lisgan then stnidae fo ognig to Ggoli it lduwo be tesn rastya ntio tscompyal, ikna ot woh ni lcI-le Dx teh yesenmz etg tens otu of hte lecl ncise ether is on ficrgankfit lanisg eeeo(frhtr I mspredeu lagre oeomsyls ude to eaignt eth aggeegdart n).opreit erA ew sagiyn tihowut COP or inCahrlt thta eth leecvis lwli yimlps syta upt wreeh it ?is fI I anc etg a plyer orebfe my emax (2 )eeswk tht'ad be cuhm edpetracipa +2

"Swelling of the ER" = Myocardial ischemia from cessation of coronary blood flow describes a stepwise process of cellular injury. One of the first manifestations of cardiomyocyte injury is swelling of the cell and its organelles, which occurs as the intracellular accumulation of sodium leads to an alteration in the osmotic gradient. If blood flow is not restored, apoptosis eventually occurs.


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 +0  upvote downvote
submitted by โˆ—abhishek021196(120)
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IIOPC elesicvs: RER to oPGOgICl i eislv:sec lGigo ot ERnatlrRiCh : iGlgo to elCl nebeamMr

etGra miaradg ot ererf - oe/pe2x80-120/t6Soj9ral-.ag0m51cs/pf/.-dem0sst.:sntn40hc0g6nc760i.t1-/

fI yynobad aswtn to ese olhrygu het eanms fo dssesaie PICIO oiutntma essacu

xn&eogc/nirvanomidspdhi?.enpoegm/ecseibc7otcertr=ttctep.icua..2/eailc/lit5avs=ttt1tew:a;tn

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