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medskool123
why not hep B? i guess another whats the better answer ones... Just rem reading that it was more common with aids pts.. anyone have an idea about this?
+1
haliburton
Yes, I think CNS lymphoma as an AIDS defining illness wins the day.
My thought was since SHE has AIDS it is most likely from IVDA, which has a high risk of HBV that could go undiagnosed for a long time. at 32, that might not be long enough to have HBV and get HCC (but with no immune system...?)
+3
yotsubato
God damn this is such BULLSHIT...
+15
sars
My thought process, usually wrong all the time, was that HBV (IVDU) can occur to anyone. Acute hepatitis to Chronic occurs when HBV incorporates its DNA into host and releases mutagenic proteins. This is regardless of immunosuppresion. Primary CNS Lymphoma reappears primarily when you are immunosuppressed (organ transplant, immunodeficiency, HIV/AIDS).
+2
syoung07
Hep C is far more likely to become HCC than hep B
+2
jurrutia
Even if you were thinking skin cancer is more common, that's only true for basal cell and squamous. Melanoma is rare. EBV much more likely in aids patient. Even H pylori was a better answer.
+
-
Lymphoma in patients with AIDS can take on many forms, but primary CNS lymphoma is common.
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It often presents with seizures, lethargy, subacute memory loss, and headache. Physical examination may show neurologic deficits stemming from structural disruption caused by the location of the mass.
- MRI will usually show a dominant cortical mass.
DDX
* Multiple lesions distributed throughout the cortex would be atypical! --> HSV enceph or Toxo
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submitted by โlsmarshall(465)
I thought this was a trick question since skin cancers are the most common type of cancers overall. But actually among HIV patients, HIV-related cancers are much more common than non-HIV-related cancers (even skin cancers). EBV-induced primary CNS lymphoma is the only option that is AIDs-defining illness/cancer.