Im also convinced blocking IL-2 is also a treatment? WHy is TNF-alpha the better answer here?
amorahFA P120-122. Immunosuppressants for RA are calcineurin inhibitor (cyclosporine and tacrolimus), 6MP, and TNFa inhibitors (adalimumab,infliximab, etanercept). It is important to distinguish that calcineurin inhibitors block t cell activation by preventing IL-2 transcription, not necessarily block IL-2 action. Sirolimus(rapamycin) blocks IL-2 action but it is used for kidney transplant rejection prophylaxis specifically. +32019-06-06T19:41:49Z
to snoo-finity ... and beyond!
submitted by seagull(362), 2019-06-01T18:07:20Z
Im also convinced blocking IL-2 is also a treatment? WHy is TNF-alpha the better answer here?