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Retired NBME 23 Answers

nbme23/Block 1/Question#45 (reveal difficulty score)
A 56-year-old woman comes to the physician ...
Presynaptic release of acetylcholine ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: msk repeat

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 +8  upvote downvote
submitted by โˆ—step420(32)
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rPoesn sah tbLae-aomtErn sedormny (hx of guln cce,arn nda umeslc tyvciiat that is beetrt hwti ue.s

panitrPceys +2aC osbadiient eevnrtp hte aeelesr fo cAH eypyapclirlnast bausece eht indtisaoeb vertnpe the ndztiloiraaepo wnhiti eht llec adn psreetnv aytscinp evlsess fo AhC omrf lnige.av

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thotcandy  uhg, I saw C+a2 dan pdtpseo h.gniktin +18
paperbackwriter  hyn@tctoda Smae heer (: +2
sidlersofcattan  ehyt tog me too iwht hatt +C+a rpi +4
psay1  01FA92 p.g 634 +1
meja2  snoseL r:ntela reda the srewna iseocch vyre alrycfeul (: uilamAyloactt tnew rof C2a+ +
chaosawaits  I esusg oyu cduol clla taht a rp.tCata l'lI ese sfmlye o.tu +1

Patients with Lambert-Eaton myasthenic syndrome (LEMS) possess antibodies to voltage-gated calcium channels on presynaptic lower motor neurons, which decreases calcium influx and acetylcholine release to postsynaptic skeletal muscle cells.

In some patients, malignancies (eg, small cell lung cancer) trigger production of these antibodies, resulting in paraneoplastic LEMS Patients present with progressive proximal muscle weakness that improves with repetitive motion and exercise.



 +0  upvote downvote
submitted by โˆ—namesthegame22(14)
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hTe pttasnopsyci mabenrem ptonateil oi(eChc D) yma eb aedredecs in LESM acseodyrn ot hte deceersad pipsyrcetan alerese of oll.ehnaicycte = GNWOR SNA.

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