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NBME 23 Answers

nbme23/Block 3/Question#23 (reveal difficulty score)
A pregnant 28-year-old woman is found to have ...
Lactotrope๐Ÿ”,๐Ÿ“บ
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 +9 
submitted by mousie(237),
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ruYo rytpatiui lctroptao selcl hrpthepyryo ruingd engpnyacr ot ucoperd gnrciaesin masnout fo pnaroclti - rapt fo eth ihhgopltosayopy of Sseen'hah .ondms..yre rindecase odblo ossl udrnig dyierevl cna ausec isicmche nscoseri fo yautpriti

tinydoc  I thought the elevated Estrogen and progesterone depress the function of Prolactin until delivery. I guess you needed to know that it decreases its function by downregulating receptors or something as opposed actually decreasing the prolactin production. I picked gonadotrophs. This was a fair question but I reasoned it out and arrived at the wrong conclusion. +8  
maxillarythirdmolar  Specifically, the estrogen is stimulating lactotrophs as progesterone is preventing the prolactin from actually working on the breasts. So it's the estrogen that is stimulating the lactotrophs to grow, and you would see the effects of this growth if it weren't for the progesterone preventing the action of prolactin (their secretory product) on the breasts. +9  
dul071  why not somatotrophs. she's understress. wouldn't that increase the production of GH +  



 +0 
submitted by haozhier(20),
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I cehso tortcpeiocro bacsuee I ghuthto ugnird geprcnnya mwone eavh reom roo.isclt nCa nyaneo niaplex ti rfo ?me h!sTkan