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Retired NBME 24 Answers

nbme24/Block 2/Question#1 (reveal difficulty score)
A 73-year-old woman has had easy fatigability ...
Failure of conversion of N5-methyltetrahydrofolate to tetrahydrofolate 🔍 / 📺 / 🌳 / 📖
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 +16  upvote downvote
submitted by syoung07(58)
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wdulo ahev eenb elra teoan if hety hetrw in a tyreendsgme-peh tpuhorline

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 +11  upvote downvote
submitted by yex(128)
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rccdgiAon ot Gjolna: 2"1B abi)naomlc( ahs blcaot ni .ti ritCacuilng rfmo of eafolt si raryealdttehylooftmhet. posrPue of omabnalci B1()2 si ot keta hte emylth orupg ffo fo lfotdlryemtayohtatere.h hnTe ’its ldleac etaoeltdtryarhfo. fI uoy ’tnod egt the yehlmt opurg off of tefo,al oyu lwli ont kaem NAD. So, fi uyo era 12B fde, uyo ’ctna egt the emthyl pguor fof adn tnocna akem AN.D fI yuo are efd ni f,aleto uoy ’cnta aekm "D.AN

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misterdoctor69  moal +

pic of the methionine/folate cycle: https://i.imgur.com/XXWXTT7.png

+2/- hungrybox(1277)


 +7  upvote downvote
submitted by lsmarshall(465)
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lhhutgAo Chrosn' yam vaeh se,ulrc utasl,isf adn egn;ibdle ti syluaul edso ont secau iron yciinfceed enmaai and sah lsse nleedgbi hnat UC. lrSatrutu"c mnaeaoiirtlbs fo the elrnmati ielu,m husc sa ohnCr ideesas dan rualcsig ncs,etieor anc cueas edsedeacr tarobposni of imianvt 1B.2" - istFr Adi ealGner eniislPcrp

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 +3  upvote downvote
submitted by lispectedwumbologist(122)
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Why wodlu ti not be mnaaie fo nrhccoi sedaies htwi eeaeddrsc surme rirfesrtann incoancot?ernt

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lispectedwumbologist  midnerNev m'I upsidt as cukf I ese ym emkista +2
drdoom  be dink to e,ylufsro doc! 'is(t a ongl oard weer' )!no +21
step1forthewin  ,Hi nac emsoeon lpiexan eht dlboo mers?a t'sni it pdspueso ot whos gehneepmseytdr ulshiontper fi it saw 1B2 deicey?cnfi +1
loftybirdman  I hinkt eth dobol msare is wnihgso a eonl yp,tmlycheo cwhih uldosh be eth seam zise sa a rnomla RBC. oYu acn ese teh BRCs in sthi smera ear bgrige ahnt atht c-iaytcmc>or -12B> finiyccdee +25
seagull  abyem 'im ewn to the gaem. btu n'its the wnsrae flaeot iinecyedfc nad otn ?21B oAsl, i ohught it was mnieaa of cirhcno eisadse sa lwel. +
vshummy  meepiowcudsgtto,lsbiL lepase nilxpae yoru tsiae?mk olL ubeseca ttha smsee klie a lptrseiecbe wasrne to ..m .e +9
gonyyong  tIs' a B21 ncueeeiicmIf d yl is erewh B12 is dboberaers, feolta si huTmn uejje dbloo mrsae si hswgino elerndag Bt ehsn MiiCRnoe tsenashy dsoe tsih snnrioce,vo uinsg tfoaoccr 21B +2
uslme123  imanAe fo chciron seadise si a cotimcricy eaamin -- I leeibve this is hwy teyh upt a thpeyoylcm on hte eisd -- so we olcdu ees taht it swa a iocmcyarct eaai.nm +4
yotsubato  akhnsT ,MNBE atth lrleya hpdeel ....me +1
keshvi  hte isonuqte saw teirylvela asy,e btu teh pcuteir asw os umidsiggni i left! i hhtutgo it oedkol leki icyrmoicct sCBR. I segus hte yek s,i ahtt yeht lyrelca noedetmni tadisl .imule adn htat si TEH tsei rfo B12 raoibpts.on +6
sahusema  I ddint' eevn egsiertr that saw a .mhpleyyotc I huhtotg I swa eesgin ettrag llsec os I was ucnedsfo AF +
drschmoctor  eeLav it ot ENMB to infd eth spatle mccsoaeytr no eth le.tanp +5
zevvyt  so i gessu siez is ermo rtnomtpai htan olrco escua ehost era picatyhocrhom as kfuc +
yesa  Teh CLNSUEU fo a ypmlceyoht hldous eb eht mesa eszi as a alronm ,BRC hciwh si tno eth esac erhe. derUn loarmn cscnitrmeacsu RBCs ear not sa gbi sa hmplyyo,stec so htsi si lytur rxirednyotaar = albgomsitclea mnieaa. +1
weirdmed51  as@ye ouy aenm ’ta‘cycioc.rm For it ot be lsgtmbaia’elc‘o rhtee had to be a ymtdeeesgerhnp ipetuorl.hn +



 +1  upvote downvote
submitted by krewfoo99(116)
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ilcfo aidc enhw it teesrn teh odyb is in hte fmor fo eahttaomttrleyyeldfhro FTH( .ye)emdlhtta tI endstao sti tyehml ropug ot iimatnv 21B to eboemc THF te(h iatecv mofr wchih as a NAD .rups)rroec eTh mivaitn 2B1 htwi tsi ylehtm gupro soeg no ot ebomicn wtih ecotoenyihm to mfro tme.eonihin

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 +1  upvote downvote
submitted by sunshinesweetheart(112)
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cirocatcmy aamnie e(nes ni bdloo es)mar = BRC copsserrru nac wgro ubt nto didive

avol eoctcramys n(ese in bodol srmea) = aolmigscebatl eiamna if( ehyt d'otn owsh lirpotneuh hynt)retpemosageni

1B2 hsa iogrueclon mtoysmps adn olw ytecmanhlmoil icad hiwle laetof edniiyfcec dose nto

olfeta is eobrdasb ni jm,jueun 21B in liemu

uscsae fo 1B2 diccnefyie = ceorniuips ma,anie gymrstcae,ot leial nees,troci ifsh awo,mrept ivemn sga

)D aiuerfl of MTFRH ;g-t&- TFH vi(a asylrftmhnetesrea = 1B2 ecneyicfid dan irccmcyoat ienaam

B) D6GP eeciidcfyn = rymocnitco cbeesua fo rcin CRB troisdcutne; pt ouldw ohws lvaaurtarisnc ysseohlim sx eridetctapip yb an oxvaiedit sertrsos

C) opyprnnrohoeiotpg sioxade fndeiceicy = cyimiocrct aieamn abesceu fo wlo mhee issenysht

)A ercd nriftenarrs = gihh irifrten = imanae fo cohrcin isesaed = rctiomyicc eimaan ecbsuea of owl niro

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cmeacham  The awy I remrembe erehw 12B iofstcnnu sthi is hatt uyo ntaw "ot 21B ahtt oeHTMr "RF +



 +1  upvote downvote
submitted by an1(114)
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saW btuao to coesoh eacrddsee rafersnintr baceeus I do'unclt ese enypd-etmeesrhg peslutrn.hoi Btu NBME nefto teirs to hrwot us off ithw aeguv .magsei So I aedr an.iga taghCu eht Iae"ll ics".renoet ronI iFst Br!o eImul si 1B2 iaprnosb.ot B21 sretusl ni aclsgmaoitble .neaima 5MN-HTF is a etsp in cionrvnetg HDF niot FT.H hdnIiebti ni cibgelmoasalt mneaia keli B12 nad B9 .efd

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an1  soAl lr,clae taht 1B2 is ertsdo orf myan saeyr. os ennegtpsri wiht a def aesyr aretl (I aereg 01 is a upjm but )iltsl si an dnriioact oot +



 +1  upvote downvote
submitted by unknown001(9)
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ohw ot ruel out niro de.f ? i nor si obdsabre ni omdudnee and xmpilaro mujjneu .

21b in eum.il

stih wlil vige ouy teh arwsen

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madamestep  I kufecd bnrita:ty Ion,r taFloe, B21 +1



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