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Retired NBME 24 Answers

nbme24/Block 2/Question#1 (reveal difficulty score)
A 73-year-old woman has had easy fatigability ...
Failure of conversion of N5-methyltetrahydrofolate to tetrahydrofolate 🔍 / 📺 / 🌳 / 📖
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 +16  upvote downvote
submitted by syoung07(58)
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wodlu veah bnee lrae oetan if they erhtw in a emsepetyndg-reh riolphtnue

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 +11  upvote downvote
submitted by yex(128)
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cgcordAni ot lo:njGa 2"1B aboam(cnl)i ahs cbtloa in .it alrucngtiCi rmfo of floeta si ertodftmlrhoy.hteyaalet ruoePsp of anomiclba (2B1) si to take teh myhelt ugorp ffo fo yrfelelhtmyoheadtroat.t enhT ti’s elcadl a.ytdfareeotlotrh fI uoy to’nd gte eht hmtyel opugr ffo of lteoaf, uyo lwli ton ekma ADN. ,So if ouy era 1B2 df,e ouy a’ntc egt eth lytemh pruog fof and contan ekma N.DA fI oyu rea edf ni oe,aflt uyo antc’ kmea ."DNA

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misterdoctor69  almo +

pic of the methionine/folate cycle: https://i.imgur.com/XXWXTT7.png

+2/- hungrybox(1277)


 +7  upvote downvote
submitted by lsmarshall(465)
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Ahthlgou Cros'nh amy aveh e,rclus a,sufslit dan i;nlbegde ti llusyua sdeo nto uaesc nroi diecfnieyc ianmae nda has ssle lgebeind atnh UC. aruuc"lSttr talrmoaiibesn of eth tamilner e,iulm cuhs sa Cnroh ssieaed dan crusailg rs,coeeint anc ceusa eadrsecde osnoipbrat of tanviim 2"B.1 - Frtis iAd laGerne slniicrpPe

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 +3  upvote downvote
submitted by lispectedwumbologist(122)
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Why would it tno eb meinaa of ichrcno sieased twih eeceadrsd smuer rnsrienfart ntc?rncooietan

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lispectedwumbologist  neeNmvird I'm usdpit sa ukfc I ese ym simaetk +2
drdoom  be kdni to ,oesrfyul cdo! it(s' a nogl ardo 'were )no! +21
step1forthewin  Hi, can oeomesn xeplina hte blood sa?mre ti'sn it seopdspu ot shwo tdengpmyehsere iplhestroun fi ti wsa 12B icceyndf?ie +1
loftybirdman  I ktnhi teh odolb saerm si owsgnih a neol mtylpoheyc, wchih osuhld eb teh mase iezs sa a almnor RBC. ouY nac ees hte BCRs in tshi measr are bgrige tnha htta coit-aym>crc B21>- cedfcyniie +25
seagull  ybmae mi' wne to the egma. utb it'ns eth eanswr lftoae icfeynecdi dan not 2B?1 o,Asl i tohhgu it swa nmaiae fo nriccho sasedei as .lwel +
vshummy  gu,isttwobmLeilopsdec asplee axnipel oyru kt?aeism lLo eceasub hatt essem ikle a eeesbrtpcil neaswr ot m. .e. +9
gonyyong  'tIs a 21B deeuncmei iylcI f is ewhre 21B is d,rseboerab ofltea si jemjh euTun bdolo amesr si wsonihg nlaregde iCenMR tsnoBh ie shsayetn esod sith nvnsroei,oc ignsu rcatocof 21B +2
uslme123  aiAmne fo riocnhc asiedse is a imctcyoirc eamani -- I ieeebvl stih si why ythe upt a cmyyhtpole on the ised -- os ew udloc see htta it swa a yccaircmto ei.anma +4
yotsubato  kTnahs M,NBE htat eyrlla lhedep .m...e +1
keshvi  hte niqestou saw eltayiverl se,ay tbu het riecput asw so snmuiidggi i le!tf i ogthtuh ti oodlek ilke ycrcoctmii CBsR. I esusg eht yke ,si tath ehyt elrclay mneeoidnt tlsdai ime.ul dan thta is HTE siet fro B21 oopisrnab.t +6
sahusema  I nd'idt nvee egstreir hatt was a yhtoplecym. I huhttgo I aws ineesg geartt lcels so I swa foecnuds FA +
drschmoctor  eLvae it ot MEBN ot idfn teh ptlesa eyroccastm no the .tlnape +5
zevvyt  so i esgus eizs si moer ntrtpoaim atnh rolco saecu stoeh are hmiraythoocpc sa kfuc +
yesa  ehT ULESCUN of a oympcehtyl ohsuld be het eams seiz sa a lornam BRC, hhciw is tno hte scea .eher eUdnr noamrl urcssmacncite CsRB rae nto sa bgi as olycme,shpty os shti si ylrtu oxynretarriad = aglbmaeclitos eaa.nim +1
weirdmed51  se@ya ouy enma t.’cria‘omycc Fro it to eb lc‘mea’aotsibgl hrtee had to be a drnmgheeeyptse euhotirp.ln +



 +1  upvote downvote
submitted by krewfoo99(115)
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cfloi icda nhew ti seenrt the oybd is ni het morf of oyaymotreltrahldttehef HFT( )dh.ytmltaee tI sanotde its lthemy gprou to tmviina 2B1 ot mbeoce THF (eht veciat ofmr ihchw as a NDA s.ue)rcropr eh T ivtamni 2B1 whit ist mhyelt gropu soeg no ot ecobnmi hwit yneotceihmo to fmro .ntheneimio

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 +1  upvote downvote
submitted by sunshinesweetheart(112)
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cacytcmior inaaem s(een in doblo eamrs) = CBR rcrupesors can wogr tbu not divied

loav trsameoccy (nsee in obdlo )mrsea = tsbciaamollge miaane f(i tehy dt'no sowh ptneiolrhu g)tmyetseannirepoh

1B2 sha giuocrleon omsytmps nad lwo moeinmltylcha cida eilhw ltaofe ncifcdeiye seod ton

oftela is sdebraob ni ju,ejmun B21 in emliu

ess cau of 12B eeycidfnic = crneusopii ,inmeaa tgemo,atrsyc elila ,eciretosn ifsh maortew,p igsm evan

)D ruifeal fo TMFRH g-;t-& HFT (aiv atrnseehetmflsary = 1B2 ieidnccyfe and matrccycio naieam

B) PDG6 iceiycdefn = cnryitcomo ucesbea of incr RBC dt;couesrnti pt udwlo wosh uaanarscitrvl omliyhess xs piarttieecpd by an ievaixdto erstsros

)C nprohpioerynpgoto osexdai eccnfyeiid = moiyctccir aiamen cueebas of wlo heme sshsnytei

A) derc aensrrntrif = high reitrnif = ameain of cnhciro dsaiese = omcicciyrt menaai scaeebu of olw roni

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cmeacham  ehT ayw I eerebmmr ewher 21B ocfnuints iths si hatt yuo nawt "to 21B ttha oTerHM "RF +



 +1  upvote downvote
submitted by an1(114)
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aWs tbauo ot oecohs cedaedsre nrnsefirart cbeaseu I dn'lctuo ese -tgedseyrnmhpee oniplhsure.t tuB BNME eontf trise ot rwoht us ffo wtih guvea m.aeigs oS I edar gnaia. Cgahut teh aIe"ll csneei.tor" oInr iFts !Bro Imleu si 1B2 b.sptooairn B21 uresslt ni bacllgsimatoe a.eiamn F-T5NMH si a epts in ringenocvt FDH toni HF.T hiidebntI in laactmelgisbo enamia kile 1B2 nad 9B dfe.

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an1  sloA r,llcea hatt 1B2 is ortsed rfo ynam r.ysae so isernntgep twhi a def eyras rtael I( eerga 01 is a umjp btu )sltil si an diticaonr oto +



 +1  upvote downvote
submitted by unknown001(9)
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who to reul tou nroi .dfe ? o nir si saobbder ni dumedone adn roalxmip jjmnuue .

1b2 ni emuil.

tsih llwi igve uyo eht warsen

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madamestep  I cedkuf tatb:nriy Ir,on taloFe, 1B2 +1



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